1044272-27-6

Basic information

• Product Name: 8-isopropyl-5-methyl-2-(3-nitro-5-trifluoromethyl-phenylamino)-7,8-dihydro-5H-pteridin-6-one
• Synonyms: 8-isopropyl-5-methyl-2-(3-nitro-5-trifluoromethyl-phenylamino)-7,8-dihydro-5H-pteridin-6-one
• CAS NO: 1044272-27-6
• Molecular Weight: 410.356
• Mol File: 1044272-27-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-isopropyl-5-methyl-2-(3-nitro-5-trifluoromethyl-phenylamino)-7,8-dihydro-5H-pteridin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-isopropyl-5-methyl-2-(3-nitro-5-trifluoromethyl-phenylamino)-7,8-dihydro-5H-pteridin-6-one(1044272-27-6)
• EPA Substance Registry System: 8-isopropyl-5-methyl-2-(3-nitro-5-trifluoromethyl-phenylamino)-7,8-dihydro-5H-pteridin-6-one(1044272-27-6)

Safety Data

• Hazardous Substances Data: 1044272-27-6(Hazardous Substances Data)

Upstream product

• 1044272-20-9 2-chloro-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one 
• 401-94-5 3-nitro-5-(trifluoromethyl)-phenylamine 

Downstream Products

• 1044272-28-7 2-(3-amino-5-trifluoromethyl-phenylamino)-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one 

Relevant articles and documents

Pteridinone derivatives as PI3-kinases inhibitors

New compounds of formula 1 are provided which by virtue of their pharmaceutical activity as PI3-kinase modulators may be used in the therapeutic field for the treatment of inflammatory or allergic diseases. Examples of these include inflammatory and allergic respiratory complaints, inflammatory diseases of the gastro-intestinal tract and motor apparatus, inflammatory and allergic skin diseases, inflammatory eye diseases, diseases of the nasal mucosa, inflammatory or allergic conditions involving autoimmune reactions or inflammations of the kidney.