10444-14-1

Basic information

• Product Name: Propanedioic acid, (2-cyanoethyl)phenyl-, diethyl ester
• CAS NO: 10444-14-1
• Molecular Formula: C16H19NO4
• Molecular Weight: 289.331
• Mol File: 10444-14-1.mol

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, (2-cyanoethyl)phenyl-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, (2-cyanoethyl)phenyl-, diethyl ester(10444-14-1)
• EPA Substance Registry System: Propanedioic acid, (2-cyanoethyl)phenyl-, diethyl ester(10444-14-1)

Safety Data

• Hazardous Substances Data: 10444-14-1(Hazardous Substances Data)

Upstream product

• 109-75-1 but-3-enenitrile 
• 83-13-6 diethyl 2-phenylmalonate 
• 542-76-7 3-Chloropropionitrile 
• 107-13-1 acrylonitrile 

Downstream Products

• 10444-25-4 4-Phenyl-5-hydroxy-pentansaeurenitril 
• 10444-31-2 2-hydroxy-5-phenyltetrahydropyran 
• 27768-60-1 ethyl 2-ethoxy-3-phenyl-3,4,5,6-tetrahydropyridine-3-carboxylate 
• 1025954-23-7 2-(3-phenyl-3,4,5,6-tetrahydro-pyridin-2-ylsulfanyl)-malonic acid diethyl ester 
• 133905-15-4 Ethyl 3-phenyl-2-thioxopiperidine-3-carboxylate 
• 1026960-99-5 2-oxo-3-phenyl-piperidine-3-carboxylic acid 
• 35576-17-1 3-Phenylpiperidine-2-thione 
• 51551-56-5 (RS)-3-phenylpiperidin-2-one 
• 738541-91-8 2-(3-Amino-propyl)-2-phenyl-malonic acid diethyl ester 
• 10444-19-6 4-cyano-2-phenylbutyric acid ethyl ester 
• 2628-87-7 2-phenylglutaric acid 
• 63378-71-2 Ethyl 2-oxo-3-phenylpiperidine-3-carboxylate 

Relevant articles and documents

Potential GABAB Receptor Antagonists. X* the Synthesis of Further Analogues of Baclofen, Phaclbfen and Saclofen

In an attempt to obtain new compounds with binding activity at the GABAB receptor site, we report the synthesis of 3-amino-2-arylpropanoic acids, and the sulfonic, phosphonic and hydroxamic acid analogues. In addition, we report the synthesis of the isomer of phaclofen, 3-amino-1-(4-chlorophenyl)-propylphosphonic acid, and the higher homologue of baclofen, 5-amino-2-(4-chlorophenyl)pentanoic acid.

Synthesis of new deazatetrahydropterins as potential NO synthase modulators

As part of our research on NO synthase modulators, a series of deazatetrahydropterins were synthesized and their effects were assessed. In this paper, we describe the synthesis of new substituted (especially at the 4a position) 2-amino-4-hydroxy-3,4,4a,5,6,7-hexahydropyrido[2,3-d]pyrimidines. These compounds showed no interesting pharmacological activity. Elsevier.