104450-63-7Relevant academic research and scientific papers
Synthesis, pharmacological activity, and chromatographic enantioseparation of new heterocyclic compounds of the aryloxyaminopropanol type derived from 4-hydroxyphenylalkanones
?i?máriková, Ru?ena,Némethy, Andrej,Habala, Ladislav,Ra?anská, Eva,Valentová, Jindra,Hroboňová, Katarína
, p. 969 - 976 (2018/05/07)
Abstract: In the paper, a series of six pharmacologically active compounds (β-adrenolytics) derived from 4-hydroxyphenylethanone and 4-hydroxyphenylpropan-1-one are reported. The compounds incorporate pyrrolidin-1-yl and 4-methylpiperazin-1-yl substituent
Synthesis and Biological Evaluation of New Combined α/β-Adrenergic Blockers
Némethy, Andrej,Vavrinec, Peter,Vavrincová-Yaghi, Diana,?epcová, Diana,Mi?úth, Svetozár,Král'ová, Eva,?i?máriková, Ru?ena,Ra?anská, Eva
, (2017/06/13)
The synthesis, characterization, and pharmacological evaluation of new aryloxyaminopropanol compounds based on substituted (4-hydroxyphenyl)ethanone with alterations in the alkoxymethyl side chain in position 2 and with 2-methoxyphenylpiperazine in the ba
4-(3-ALKYLAMINO-2-HYDROXYPROPOXY)-3-(ALKOXYMETHYL)ACETOPHENONES
Cizmarikova, Ruzena,Borovansky, Alois,Kozlovsky, Jan,Bederova, Eva,Dingova, Anna
, p. 2289 - 2298 (2007/10/02)
A series of new beta-adrenolytics derived from p-hydroxyacetophenone was synthesized by four methods.The most advantageous was found to be the five-step synthesis via reaction of the intermediate oxirane with amines.The selected compounds reveal a beta-ad
