104450-78-4

Upstream product

• 104450-73-9 1-(4-hydroxy-3-propoxymethylphenyl)ethanone 
• 106-89-8 epichlorohydrin 
• 99-93-4 4-Hydroxyacetophenone 
• 24085-05-0 1-(3-chloromethyl-4-hydroxyphenyl)ethanone 

Downstream Products

• 126014-59-3 1-[4-(3-bromo-2-hydroxy-propoxy)-3-propoxymethyl-phenyl]-ethanone 
• 104449-99-2 1-[4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-propoxymethyl-phenyl]-ethanone 
• 104449-98-1 1-[4-(2-Hydroxy-3-isopropylamino-propoxy)-3-propoxymethyl-phenyl]-ethanone 

Relevant academic research and scientific papers

Synthesis and Biological Evaluation of New Combined α/β-Adrenergic Blockers

The synthesis, characterization, and pharmacological evaluation of new aryloxyaminopropanol compounds based on substituted (4-hydroxyphenyl)ethanone with alterations in the alkoxymethyl side chain in position 2 and with 2-methoxyphenylpiperazine in the ba

Synthesis, pharmacological activity and chromatographic separation of some novel potential β-blockers of the aryloxyaminopropanol type

Following our previous structure-activity relationship studies, some novel compounds of the aryloxyaminopropanol type, derived from 2- or 4-hydroxyphenylalkanones, with phenethyl or 3,4-dimethoxyphenethyl groups in the hydrophilic part of the molecule wer

4-(3-ALKYLAMINO-2-HYDROXYPROPOXY)-3-(ALKOXYMETHYL)ACETOPHENONES

A series of new beta-adrenolytics derived from p-hydroxyacetophenone was synthesized by four methods.The most advantageous was found to be the five-step synthesis via reaction of the intermediate oxirane with amines.The selected compounds reveal a beta-ad