1044505-27-2Relevant academic research and scientific papers
UNA AMIDITES AND USES THEREOF
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, (2020/12/29)
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a disease which utilize a composition or
UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability
Langkjaer, Niels,Pasternak, Anna,Wengel, Jesper
experimental part, p. 5420 - 5425 (2009/12/06)
UNA (unlocked nucleic acid) monomers are acyclic derivatives of RNA lacking the C2′-C3′-bond of the ribose ring of RNA. Synthesis of phosphoramidite UNA building blocks of the nucleobases adenine, cytosine, guanine, and uracil is described herein together
Synthesis and biological evaluation of novel selenonucleosides
Chen, Yao,Peng, Yingdan,Zhang, Jiancun,Fu, Lei
, p. 1001 - 1008 (2008/12/22)
A series of novel selenonucleoside analogues with 1,4-oxaselenane as the carbohydrate fragment has been synthesized from their corresponding dimesylated seconucleosides treated with NaHSe solution and subsequent deprotection. The synthesized selenonucleos
