1120329-60-3

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 64350-24-9 N²-isobutyryl-2'-deoxyguanosine 
• 81246-83-5 9-(5-O-dimethoxytrityl-β-D-ribofuranosyl)-2-N-isobutyrylguanine 
• 1044505-27-2 5'-O-(4,4'-dimethoxytrityl)-2-N-isobutyryl-2',3'-secoguanosine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1120329-61-4 2'-O-benzoyl-3'-O-(2-cyanoethoxy(diisopropylamino)-phosphino)-5'-O-(4,4'-dimethoxytrityl)-2-N-isobutyryl-2',3'-secoguanosine 

Relevant academic research and scientific papers

UNA AMIDITES AND USES THEREOF

Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a disease which utilize a composition or

UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability

UNA (unlocked nucleic acid) monomers are acyclic derivatives of RNA lacking the C2′-C3′-bond of the ribose ring of RNA. Synthesis of phosphoramidite UNA building blocks of the nucleobases adenine, cytosine, guanine, and uracil is described herein together