1044535-52-5 Usage
Uses
Used in Pharmaceutical Industry:
(4bS,7R,8aR)-4b-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-4b,5,6,7,8,8a,9,10-octahydrophenanthrene-2-carboxamide is used as a selective high-affinity partial agonist of the glucocorticoid receptor for the treatment of various diseases. Its unique structure allows it to modulate the activity of the glucocorticoid receptor, offering a targeted approach to disease management.
Used in Drug Development:
(4bS,7R,8aR)-4b-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-4b,5,6,7,8,8a,9,10-octahydrophenanthrene-2-carboxamide can be utilized in drug development as a lead molecule for the design of new therapeutic agents. Its specific interactions with biological targets, such as the glucocorticoid receptor, make it a promising candidate for the treatment of various conditions, including inflammatory and autoimmune diseases.
Used in Chemical Research:
(4bS,7R,8aR)-4b-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-4b,5,6,7,8,8a,9,10-octahydrophenanthrene-2-carboxamide can also be employed in chemical research to study the effects of molecular structure on biological activity. Its unique features, such as the trifluoromethyl group and the hydroxyl group, can provide insights into the design of more effective and selective drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 1044535-52-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,4,5,3 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1044535-52:
(9*1)+(8*0)+(7*4)+(6*4)+(5*5)+(4*3)+(3*5)+(2*5)+(1*2)=125
125 % 10 = 5
So 1044535-52-5 is a valid CAS Registry Number.
1044535-52-5Relevant academic research and scientific papers
Tricyclic Compound, Compositions, and Methods
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Page/Page column 13; 18, (2008/12/07)
The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
