305830-57-3

Upstream product

• 1044535-50-3 methyl (4βS,8αR)-4β-benzyl-7-oxo-4β,5,6,7,8,8α,9,10-octahydrophenanthrene-2-carboxylate 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 1400926-92-2 (S)-4a-benzyl-7-bromo-4,4a,9,10-tetrahydrophenanthren-2(3H)-one 
• 418772-23-3 (1R,9S,10R)-1-benzyl-5-bromo-10-hydroxy-10-methyl-tricyclo[7.3.1.0(2,7)]trideca-2,4,6-trien-13-one1(R)-benzyl-5-bromo-10(R)-hydroxy-10-methyl-tricyclo[7.3.1.0_2,7]trideca-2,4,6-trien-13-one 

Downstream Products

• 1044535-52-5 (4bS,7R,8aR)-4b-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-4b,5,6,7,8,8a,9,10-octahydrophenanthrene-2-carboxamide 
• 1044589-16-3 (4βS,7R,8αS)-4β-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-4β,5,6,7,8,8α-hexahydrophenanthrene-2-carboxamide 
• 1400925-73-6 (7aR,9R,11aS)-11a-benzyl-9-hydroxy-N-(2-methylpyridin-3-yl)-5-oxo-9-(trifluoromethyl)-5,7,7a,8,9,10,11,11a-octahydrodibenzo[c,e]oxepine-3-carboxamide 
• 1400925-75-8 (3R,4aR,11bS)-11b-benzyl-3-hydroxy-6-methyl-N-(2-methylpyridin-3-yl)-3-(trifluoromethyl)-2,3,4,4a,5,6,7,11b-octahydro-1H-dibenzo[c,e]azepine-9-carboxamide 
• 1400927-13-0 4-((1S,2R,4R)-1-benzyl-4-hydroxy-2-(hydroxymethyl)-4-(trifluoromethyl)cyclohexyl)-3-(hydroxymethyl)-N-(2-methylpyridin-3-yl)benzamide 
• 1400925-74-7 (7aR,9R,11aS)-11a-benzyl-9-hydroxy-N-(2-methylpyridin-3-yl)-9-(trifluoromethyl)-5,7,7a,8,9,10,11,11a-octahydrodibenzo[c,e]oxepine-3-carboxamide 
• 1400927-17-4 (4bS,7R,8aS)-4b-benzyl-10-methyl-N-(2-methylpyridin-3-yl)-7-(triethylsilyloxy)-7-(trifluoromethyl)-4b,5,6,7,8,8a-hexahydrophenanthrene-2-carboxamide 
• 1400927-11-8 (4bS,7R,8aR)-methyl 4b-benzyl-7,10-dihydroxy-7-(trifluoromethyl)-4b,5,6,7,8,8a,9,10-octahydrophenanthrene-2-carboxylate 
• 1400927-12-9 (4bS,7R,8aS)-methyl 4b-benzyl-7-hydroxy-7-(trifluoromethyl)-4b,5,6,7,8,8a-hexahydrophenanthrene-2-carboxylate 
• 1400927-81-2 C₂₉H₂₇F₃N₂O₄ 
• 1400927-15-2 (4bS,7R,8aS)-methyl 4b-benzyl-7-hydroxy-10-methyl-7-(trifluoromethyl)-4b,5,6,7,8,8a-hexahydrophenanthrene-2-carboxylate 
• 1400927-16-3 (4bS,7R,8aS)-methyl 4b-benzyl-10-methyl-7-(triethylsilyloxy)-7-(trifluoromethyl)-4b,5,6,7,8,8a-hexahydrophenanthrene-2-carboxylate 
• 1400927-18-5 (7aR,9R,11aS)-11a-benzyl-7-hydroxy-5-oxo-9-triethylsilanyloxy-9-trifluoromethyl-6,7,7a,8,9,10,11,11a-octahydro-5H-dibenzo[a,c]cycloheptene-3-carboxylic acid (2-methyl-pyridin-3-yl)-amide 
• 1400927-19-6 (7aS,9R,11aS)-11a-benzyl-9-hydroxy-5-oxo-9-trifluoromethyl-7a,8,9,10,11,11a-hexahydro-5H-dibenzo[a,c]cycloheptene-3-carboxylic acid (2-methyl-pyridin-3-yl)-amide 

Relevant academic research and scientific papers

GLUCOCORTICOID RECEPTOR MODULATORS

The present invention provides non-steroidal compounds of formula I which are selective modulators (i.e., agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides pharmaceutical compos

Nuclear Hormone Receptor Modulators

The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treati

Tricyclic Compound, Compositions, and Methods

The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.