1044637-65-1 Usage
General Description
1-(Cyclopentylcarbonyl)-2-piperidine-carboxylic acid is a chemical compound with the molecular formula C14H21NO3. It is a piperidine derivative with a cyclopentylcarbonyl group attached to the 1-position and a carboxylic acid group attached to the 2-position. 1-(Cyclopentylcarbonyl)-2-piperidine-carboxylic acid is commonly used in the synthesis of pharmaceutical drugs and has potential therapeutic applications. It is important to note that this compound should be handled with caution and in accordance with proper safety protocols due to its potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 1044637-65-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,4,6,3 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1044637-65:
(9*1)+(8*0)+(7*4)+(6*4)+(5*6)+(4*3)+(3*7)+(2*6)+(1*5)=141
141 % 10 = 1
So 1044637-65-1 is a valid CAS Registry Number.
1044637-65-1Relevant articles and documents
Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonists
Lamb, Jeffrey P.,Engers, Darren W.,Niswender, Colleen M.,Rodriguez, Alice L.,Venable, Daryl F.,Conn, Jeffrey P.,Lindsley, Craig W.
, p. 2711 - 2714 (2011/06/20)
This Letter describes a chemical lead optimization campaign directed at a weak mGlu5 NAM discovered while developing SAR for the mGlu 5 PAM, ADX-47273. An iterative parallel synthesis effort discovered multiple, subtle molecular switches that afford potent mGlu5 NAMs, mGlu5 PAMs as well as mGlu5 partial antagonists.
