10447-11-7

Basic information

• Product Name: 4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE
• Synonyms: 1-Naphthalenesulfonylchloride, 4-Methyl-;4-Methylnaphthalene-1-sulfonyl chloride;4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE;4-METHYL-1-NAPHTHALENESULPHONYL CHLORIDE;4-Methylnaphthalene-1-sulphonyl chloride;1-(Chlorosulphonyl)-4-methylnaphthalene
• CAS NO: 10447-11-7
• Molecular Formula: C₁₁H₉ClO₂S
• Molecular Weight: 240.71
• Mol File: 10447-11-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 80 °C
• Boiling Point: 353.2 °C at 760 mmHg
• Flash Point: 167.4 °C
• Appearance: /
• Density: 1.363 g/cm³
• Vapor Pressure: 7.43E-05mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE(10447-11-7)
• EPA Substance Registry System: 4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE(10447-11-7)

Safety Data

• Hazard Codes: Xi
• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 3261
• Hazardous Substances Data: 10447-11-7(Hazardous Substances Data)

Usage

Description

4-Methyl-1-naphthalenesulfonyl chloride, also known as 4-Methyl-1-naphthalenesulfonamide chloride, is a chemical compound that serves as a reagent in organic synthesis. It is characterized by a sulfonyl chloride functional group, which consists of a sulfonyl center attached to a chlorine atom. 4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE is recognized for its versatility in the synthesis of a range of organic compounds.

Uses

Used in Pharmaceutical and Agrochemical Industries:
4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE is used as a key intermediate for the synthesis of various pharmaceuticals and agrochemicals. Its reactivity and functional group compatibility make it suitable for the development of new drugs and agricultural chemicals.
Used in Dye and Pigment Production:
In the dye and pigment industry, 4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE is utilized as a precursor in the production of dyes and pigments. Its chemical structure contributes to the color properties and stability of the final products.
Used in the Synthesis of Fluorescent Whitening Agents and Optical Brighteners:
4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE is employed as a versatile intermediate in the synthesis of fluorescent whitening agents and optical brighteners. Its unique chemical properties allow for the creation of compounds that enhance the appearance of materials by reflecting light more effectively.
Used in the Production of Resins, Plastics, and Industrial Materials:
4-METHYL-1-NAPHTHALENESULFONYL CHLORIDE is used as a component in the production of resins, plastics, and other industrial materials. Its inclusion in these materials can improve their performance characteristics, such as durability and resistance to environmental factors.

InChI:InChI=1/C11H9ClO2S/c1-8-6-7-11(15(12,13)14)10-5-3-2-4-9(8)10/h2-7H,1H3

Upstream product

• 90-12-0 1-Methylnaphthalene 

Downstream Products

• 849948-79-4 (S)-4-methylnaphthalene-1-sulfonic acid [3-(N-Boc-amino)-1-benzylcarbamoylpropyl]amide 
• 849948-78-3 4-(N-Boc-amino)-N'-((S)-1-carbamoyl-2-phenylethyl)-(S)-2-(N''-(4-methyl-1-naphthalenesulfonyl)amino)butanamide 
• 849948-73-8 4-(N-Boc-amino)-N'-(2-(3-chlorophenyl)ethyl)-(S)-2-(N''-(4-methyl-1-naphthalenesulfonyl)amino)butanamide 
• 723308-78-9 4-methyl-naphthalene-1-sulfonic acid cyclohexylamide 
• 263153-02-2 6-methyl-2-(phenylmethyl)-2H-naphth[1,8-cd]isothiazole 1,1-oxide 
• 915714-25-9 (S)-4-methylnaphthalene-1-sulfonic acid [1-benzyloxymethyl-3-(N,N'-bis(Boc)guanidinyl)propyl]amide 
• 915713-08-5 (S)-4-methylnaphthalene-1-sulfonic acid (1-benzyloxymethyl-3-guanidinylpropyl)amide 
• 915713-07-4 (S)-4-methylnaphthalene-1-sulfonic acid (3-amino-1-benzyl-oxymethylpropyl)amide 
• 915714-24-8 (S)-4-methylnaphthalene-1-sulfonic acid [3-(N-Boc-amino)-1-benzyloxymethylpropyl]amide 
• 915714-19-1 (S)-4-methylnaphthalene-1-sulfonic acid [4-(N-Z-amino)-1-benzylsulfanylmethylbutyl]amide 
• 10447-10-6 4-Methylnaphthalene-1-sulfonamide 

Relevant articles and documents

A practical and efficient preparation of the releasable naphthosultam side chain of a novel anti-MRSA carbapenem

A practical large-scale synthesis of the naphthosultam-based side chain of the anti-MRSA antibiotic 1 has been achieved in 29% overall yield over seven steps from 1-methylnaphthalene. The synthesis was completed without the use of protecting groups, featu