849948-79-4

Upstream product

• 10447-11-7 4-methyl-1-naphthalenesulfonyl chloride 
• 456527-46-1 (S)-2-amino-N-benzyl-4-(N'-Boc-amino)butanamide 

Downstream Products

• 915713-06-3 (S)-4-methylnaphthalene-1-sulfonic acid (3-amino-1-benzylaminomethylpropyl)amide 
• 849948-09-0 4-amino-N-benzyl-(S)-2-(N'-(4-methyl-1-naphthalenesulfonyl)amino)butanamide 

Relevant academic research and scientific papers

PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4

The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein A, D, E, J, Q1 R1 , R2, R3, p and j are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes sst1 and/or sst4 and can be used for the treatment or diagnosis of diseases or conditions wherein sst1 and/or sst4 agonists or antagonists are indicated to be useful.

SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS

The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein R1, R2, R3, A, B, D, Q, k and n are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes SSTR1 and/or SSTR4 and can be used for the treatment or diagnosis of diseases or conditions wherein an interaction with SSTR1 and/or SSTR4 is indicated to be useful.