10447-29-7

Basic information

• Product Name: Ethyl quinoline-4-carboxylate
• Synonyms: Ethyl quinoline-4-carboxylate;4-Quinolinecarboxylic acid, ethyl ester
• CAS NO: 10447-29-7
• Molecular Formula: C₁₂H₁₁NO₂
• Molecular Weight: 201.224
• Mol File: 10447-29-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 155-157 °C(Solv: benzene (71-43-2))
• Boiling Point: 317.3°Cat760mmHg
• Flash Point: 145.7°C
• Appearance: /
• Density: 1.175g/cm³
• Vapor Pressure: 0.000388mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.88±0.13(Predicted)
• CAS DataBase Reference: Ethyl quinoline-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl quinoline-4-carboxylate(10447-29-7)
• EPA Substance Registry System: Ethyl quinoline-4-carboxylate(10447-29-7)

Safety Data

• Hazardous Substances Data: 10447-29-7(Hazardous Substances Data)

Usage

General Description

Ethyl quinoline-4-carboxylate is a chemical compound with the molecular formula C13H11NO2. It is a derivative of quinoline, a heterocyclic aromatic compound. Ethyl quinoline-4-carboxylate is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has been found to exhibit various biological activities, including antitumor, antibacterial, and antifungal properties. The compound is also used in the flavor and fragrance industry, as it contributes to the aroma of certain compounds. Overall, ethyl quinoline-4-carboxylate has several important industrial applications and biological activities, making it a valuable chemical compound in various fields of science and industry.

InChI:InChI=1/C12H11NO2/c1-2-15-12(14)10-7-8-13-11-6-4-3-5-9(10)11/h3-8H,2H2,1H3

Upstream product

• 64-17-5 ethanol 
• 486-74-8 4-quinolinic acid 
• 91-56-5 indole-2,3-dione 
• 69564-74-5 1-vinylindoline-2,3-dione 
• 5467-57-2 2-chloroquinoline-4-carboxylic acid 
• 15733-89-8 2-hydroxyquinoline-4-carboxylic acid 
• 5467-61-8 ethyl ester of 2-chlorocinchoninic acid 
• 855166-61-9 2-iodo-quinoline-4-carboxylic acid 
• 5323-57-9 quinoline-2,4-dicarboxylic acid 
• 3964-04-3 4-bromoquinoline 
• 56-57-5 4-nitroquinoline-N-oxide 
• 22614-98-8 4-bromoquinoline-N-oxide 
• 2973-27-5 quinoline-4-carbonitrile 
• 563-17-7 potassium ethyl sulfate 

Downstream Products

• 109646-41-5 quinoline-4-carboxylic acid-(2-benzo[1,3]dioxol-5-yl-1-methyl-ethylamide) 
• 54885-00-6 phenyl(quinolin-4-yl)methanone 
• 106473-25-0 3-[4]quinolyl-3-oxo-propionic acid ethyl ester 
• 83629-96-3 1-(quinolin-4-yl)propan-1-one 
• 56153-32-3 4-ethoxycarbonyl-1-methyl-quinolinium; iodide 
• 855605-82-2 1-[4]quinolyl-2-phenyl-ethanone 
• 6281-32-9 4-quinolylmethanol 
• 4363-95-5 quinoline-4-carboxamide 
• 29620-62-0 cinchoninic hydrazide 
• 24562-76-3 Ethyl 1,2,3,4-tetrahydroquinoline-4-carboxylate 
• 110435-99-9 diphenyl(quinolin-4-yl)methanol 
• 83255-81-6 ethyl 2-cyclohexyl-4-quinolinecarboxylate 

Relevant articles and documents

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SYNTHESIS OF QUINOLINE-4-CARBOXYLIC ACID AND ITS DERIVATIVES

2-Methylquinoline-4-carboxylic acid was obtained by the reaction of isatin with acetone in the presence of alkali.This acid was converted through a step involving (E)-2-styrylquinoline-4-carboxylic acid to quinoline-2,4-dicarboxylic acid, from which quinoline-4-carboxylic acid was obtained by refluxing in nitrobenzene.The structures of the synthesized compounds were confirmed by 1H NMR spectroscopy using two-dimensional (2DJ) spectra.

HOMOLYTIC ALKOXYCARBONYLATION REACTIONS IN TWO-PHASE SYSTEMS, PART II. STUDIES ON THE ETHOXYCARBONYLATION OF SOME SELECTED ?-DEFICIENT N-HETEROAROMATIC SYSTEMS

A systematic study on the homolytic substitution of pyridine, quinoline and pyrazine by ethoxycarbonyl radicals was performed.It is demonstrated that under appropriate conditions Minisci-type alkoxycarbonylation reactions can provide convenient access to heteroaromatic monocarboxylic acid esters, like alkyl 2-pyrazinecarboxylates and alkyl 4-alkyl-2-pyridinecarboxylates.