1044733-21-2Relevant academic research and scientific papers
IRAK-4 inhibitors. Part III: A series of imidazo[1,2-a]pyridines
Buckley, George M.,Fosbeary, Richard,Fraser, Joanne L.,Gowers, Lewis,Higueruelo, Alicia P.,James, Lynwen A.,Jenkins, Kerry,Mack, Stephen R.,Morgan, Trevor,Parry, David M.,Pitt, William R.,Rausch, Oliver,Richard, Marianna D.,Sabin, Verity
scheme or table, p. 3656 - 3660 (2009/04/10)
Following the identification of a potent IRAK inhibitor through routine project cross screening, a novel class of IRAK-4 inhibitor was established. The SAR of imidazo[1,2-a]pyridino-pyridines and benzimidazolo-pyridines was explored.
