1044741-30-1

Basic information

• Product Name: tert-butyl 2-diazo-3-hydroxy-3-(2-iodo-3-methylphenyl)propionate
• Synonyms: tert-butyl 2-diazo-3-hydroxy-3-(2-iodo-3-methylphenyl)propionate
• CAS NO: 1044741-30-1
• Molecular Weight: 388.205
• Mol File: 1044741-30-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-diazo-3-hydroxy-3-(2-iodo-3-methylphenyl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-diazo-3-hydroxy-3-(2-iodo-3-methylphenyl)propionate(1044741-30-1)
• EPA Substance Registry System: tert-butyl 2-diazo-3-hydroxy-3-(2-iodo-3-methylphenyl)propionate(1044741-30-1)

Safety Data

• Hazardous Substances Data: 1044741-30-1(Hazardous Substances Data)

Upstream product

• 1694-31-1 tert-butyl acetoacetate 
• 100130-55-0 2-iodo-3-methylbenzaldehyde 

Downstream Products

• 1044741-37-8 tert-butyl 3-(tert-butyldimethylsilyloxy)-2-diazo-3-(2-iodo-3-methylphenyl)propionate 

Relevant articles and documents

Novel synthesis of cinnolines and 1-aminoindolines via Cu-catalyzed intramolecular N-arylation of hydrazines and hydrazones prepared from 3-haloaryl-3-hydroxy-2-diazopropanoates

(Chemical Equation Presented) A new and facile access to cinnolines, dihydrocinnolines, and 1-aminoindolines was established by use of diazo functionalities. The hydrazines and hydrazones as cyclization precursors derived from 3-haloaryl-3-hydroxy-2-diazopropanoates, which are prepared by one-pot procedure utilizing phase-transfer catalysis, are successfully converted to the corresponding nitrogen heterocycle by Cu-catalyzed N-arylation. Furthermore, analysis of UV spectra proved that 4-oxo-3-carboxylates predominantly exist not as 4-hydroxycinnoline (enol form) but as cinnolone (keto form).