1044749-05-4Relevant academic research and scientific papers
Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3 H)-ones: Effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes
Rotili, Dante,Tarantino, Domenico,Nawrozkij, Maxim B.,Babushkin, Alexandre S.,Botta, Giorgia,Marrocco, Biagina,Cirilli, Roberto,Menta, Sergio,Badia, Roger,Crespan, Emmanuele,Ballante, Flavio,Ragno, Rino,Esté, José A.,Maga, Giovanni,Mai, Antonello
, p. 5212 - 5225 (2014/07/08)
A comparison of the effects of the 6-(2-chloro-6-fluorobenzyl)-2- (alkylthio)pyrimidin-4(3H)-ones (2-Cl-6-F-S-DABOs) 7-12 and the related 6-(2,6-difluorobenzyl) counterparts 13-15 in HIV-1 infected cells and in the HIV-1 reverse transcriptase (RT) assays
5-alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure - Activity relationship profile
Nawrozkij, Maxim B.,Rotili, Dante,Tarantino, Domenico,Botta, Giorgia,Eremiychuk, Alexandre S.,Musmuca, Ira,Ragno, Rino,Samuele, Alberta,Zanoli, Samantha,Armand-Ugón, Mercedes,Clotet-Codina, Imma,Novakov, Ivan A.,Orlinson, Boris S.,Maga, Giovanni,Esté, José A.,Artico, Marino,Mai, Antonello
experimental part, p. 4641 - 4652 (2009/07/04)
A series of dihydro-alkylthio-benzyl-oxopyrimidines (S-DABOs) bearing a 2-aryl-2-oxoethylsulfanyl chain at pyrimidine C2, an alkyl group at C5, and a 2,6-dichloro-, 2-chloro-6-fluoro-, and 2,6-difluoro-benzyl substitution at C6 (oxophenethyl-S-DABOs, 6-8)
