889658-62-2

Upstream product

• 502506-68-5 ethyl 4-(2-chloro-6-fluorophenyl)-3-oxobutanoate 
• 17356-08-0 thiourea 
• 1242134-27-5 6-(6-chloro-2-fluorobenzyl)-2-{[(methylsulfanyl)methyl]sulfanyl}pyrimidin-4(3H)-one 
• 1044749-05-4 C₁₁H₈ClFN₂O 
• 37777-76-7 2-chloro-6-fluoro-phenylacetic acid 

Downstream Products

• 1044748-81-3 C₁₉H₁₄ClFN₂O₂S 
• 1044748-82-4 C₁₉H₁₃ClF₂N₂O₂S 
• 1044748-83-5 C₂₀H₁₆ClFN₂O₃S 
• 1242134-27-5 6-(6-chloro-2-fluorobenzyl)-2-{[(methylsulfanyl)methyl]sulfanyl}pyrimidin-4(3H)-one 
• 1242134-28-6 2-{[(allylsulfanyl)methyl]sulfanyl}-6-(6-chloro-2-fluorobenzyl)-5-methylpyrimidin-4(3H)-one 
• 1613668-95-3 6-[(2-chloro-6-fluorophenyl)methyl]-2-cyclopentylthiopyrimidin-4(3H)-one 
• 1613668-91-9 6-[(2-chloro-6-fluorophenyl)methyl]-2-isopropylthiopyrimidin-4(3H)-one 
• 1613668-94-2 6-[(2-chloro-6-fluorophenyl)methyl]-2-butylthiopyrimidin-4(3H)-one 
• 1613668-92-0 6-[(2-chloro-6-fluorophenyl)methyl]-2-propylthiopyrimidin-4(3H)-one 
• 1613668-93-1 6-[(2-chloro-6-fluorophenyl)methyl]-2-sec-butylthiopyrimidin-4(3H)-one 
• 1242134-30-0 2-(methylsulfanyl)-6-(2-fluoro-6-chlorobenzyl)pyrimidin-4(3H)-one 
• 1262963-62-1 6-(2-fluoro-6-chlorobenzyl)pyrimidin-2,4(1H,3H)-dione 

Relevant academic research and scientific papers

Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3 H)-ones: Effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes

A comparison of the effects of the 6-(2-chloro-6-fluorobenzyl)-2- (alkylthio)pyrimidin-4(3H)-ones (2-Cl-6-F-S-DABOs) 7-12 and the related 6-(2,6-difluorobenzyl) counterparts 13-15 in HIV-1 infected cells and in the HIV-1 reverse transcriptase (RT) assays

The specific character of the reaction of derivatives of 2-thioxo-2,3-dihydropyrimidin-4(1H)-one with iodomethane and alkyl chloromethyl sulfides

The alkylation of 5-alkyl-6-(2,6-dihalobenzyl)-2-thioxo-2,3- dihydropyrimidin-4(1H)-ones with MeI, AllSCH2Cl, and MeSCH 2Cl in the K2CO3-DMF, NaOMe-MeOH, and KOH-EtOH systems was investigated. A hypothetical mec

5-alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure - Activity relationship profile

A series of dihydro-alkylthio-benzyl-oxopyrimidines (S-DABOs) bearing a 2-aryl-2-oxoethylsulfanyl chain at pyrimidine C2, an alkyl group at C5, and a 2,6-dichloro-, 2-chloro-6-fluoro-, and 2,6-difluoro-benzyl substitution at C6 (oxophenethyl-S-DABOs, 6-8)