104485-82-7

Basic information

• Product Name: 7-Oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid, monomethyl ester, (1S,2R,3S,4R)-
• CAS NO: 104485-82-7
• Molecular Formula: C9H10O5
• Molecular Weight: 198.175
• Mol File: 104485-82-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 7-Oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid, monomethyl ester, (1S,2R,3S,4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid, monomethyl ester, (1S,2R,3S,4R)-(104485-82-7)
• EPA Substance Registry System: 7-Oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid, monomethyl ester, (1S,2R,3S,4R)-(104485-82-7)

Safety Data

• Hazardous Substances Data: 104485-82-7(Hazardous Substances Data)

Upstream product

• 6118-51-0 exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride 
• 67-56-1 methanol 

Downstream Products

• 5744-38-7 dimethyl 3,8-dioxatricyclo[3.2.1.02,4]octane-6,7-dicarboxylate 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 

Relevant articles and documents

Synthesis of cinchona alkaloid sulfonamide polymers as sustainable catalysts for the enantioselective desymmetrization of cyclic anhydrides

The Mizoroki-Heck polymerization of cinchona-based sulfonamide dimers and aromatic diiodides was investigated in the presence of a palladium catalyst, to obtain chiral polymers in high yields. An iodobenzenesulfonamide derivative of a cinchona alkaloid was also polymerized via self-polycondensation under the same reaction conditions. The catalytic activities of these chiral polymers were examined by using them as catalysts in the enantioselective desymmetrization of cyclic anhydrides.

Novel amide-functionalized chloramphenicol base bifunctional organocatalysts for enantioselective alcoholysis of meso-cyclic anhydrides

A family of novel chloramphenicol base-amide organocatalysts possessing a NH functionality at C-1 position as monodentate hydrogen bond donor were developed and evaluated for enantioselective organocatalytic alcoholysis of meso-cyclic anhydrides. These structural diversified organocatalysts were found to induce high enantioselectivity in alcoholysis of anhydrides and was successfully applied to the asymmetric synthesis of (S)-GABOB.

A new synthon for the synthesis of aminoinositol derivatives

The regio- and stereoselective synthesis of a new synthon, trans-3,8-dioxatricyclo[3.2.1.02,4]octane-6,7-diamine, from 7-oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate is reported. Transformation of the acid functionalities to acyl azides followed by Curtius rearrangement gave the corresponding trans-diisocyanate, which was reacted with HCl to produce a trans-diamino compound that is a potentially important synthon for the versatile synthesis of aminocyclitols.