104501-82-8Relevant academic research and scientific papers
Facile Syntheses of gem-Difluoroalkenes from Chlorodifluoromethylketones
Begue, Jean-Pierre,Bonnet-Delpon, Daniele,Percy, Jonathan M.,Rock, Michael H.,Wilkes, Robin D.
, p. 1857 - 1858 (1995)
Chlorodifluoromethyl ketones reacted with diazomethane to afford epoxides in high yield; upon treatment with butyllithium, the epoxides underwent efficient ring opening to afford 3,3-difluoro-2-alkyl-alken-1-ols, suitable substrates for sigmatropic rearra
SYNTHESES OF β,β-DIFLUOROCARBOXYLIC ACID DERIVATIVES THROUGH THE CLAISEN REARRANGEMENT OF 1,1-DIFLUORO-1-ALKEN-3-OLS
Taguchi, Takeo,Morikawa, Tsutomu,Kitagawa, Osamu,Mishima, Takashi,Kobayashi, Yoshiro
, p. 5137 - 5140 (2007/10/02)
3,3-Difluoro-4-alkenoic esters (3) were obtained through the Claisen rearrangement of 1,1-difluoro-1-alken-3-ols (1) with ortho ester.Keywords-Claisen rearrangement; 1,1-difluoroethene; dibromodifluoromethane; trimethyl orthoacetate
