1045602-14-9Relevant academic research and scientific papers
Metal Free Mono- and 2,3-Bis-sulfenylation of Indoles in Water with Sodium Sulfinates as a Sulfur Source
Liu, Changqing,Fan, Jian,Wu, Manyi,Chen, Jiahui,Zhao, Yiming,Xie, Meihua
, p. 819 - 825 (2018/07/30)
An iodine-PPh3 mediated sulfenylation of indoles in water with stable and odorless sodium sulfinates as the sulfur source is described. The reaction could afford monosulfenylated indoles in moderate to excellent yields under metal free conditions. Moreover, double C—H sulfenylation of indoles at 2- and 3-positions has also been achieved by using excess sodium sulfinates under the optimized reaction conditions.
Sodium Iodide (NaI)-Catalyzed Cross-Coupling for C?S Bond Formation via Oxidative Dehydrogenation: Cheap, Direct Access to Unsymmetrical Aryl Sulfides
Wang, Hui-Hong,Shi, Tao,Gao, Wei-Wei,Wang, Yong-Qiang,Li, Jun-Fang,Jiang, Yi,Hou, Yong Sheng,Chen, Chen,Peng, Xue,Wang, Zhen
supporting information, p. 2675 - 2679 (2017/10/18)
A simple and practical NaI-catalyzed direct C?H sulfenylation of arenes has been developed under air. In this reaction, aryl sulfides were obtained in moderate to excellent yields with high regioselectivity from readily available aromatic compounds and aryl/alkyl thiols, even on gram scale. To demonstrate the practicability of this reaction, two bioactive compound skeletons were synthesized in good yields. This method can also be used to late-stage modification of curcumin.
Copper-catalyzed sulfenylation of pyrroles with disulfides or thiols: Directly synthesis of sulfenyl pyrroles
Alves, Diego,Lara, Renata G.,Contreira, Maria E.,Radatz, Cátia S.,Duarte, Luis F.B.,Perin, Gelson
experimental part, p. 3364 - 3368 (2012/07/28)
We present here the synthesis of sulfenyl pyrroles by copper-catalyzed sulfenylation of pyrroles with organic disulfides or thiols. The direct sulfenylation of pyrroles with organic disulfides has been accomplished in the presence of 3 mol % of CuI in DMS
Asymmetric oxidation of 2-(arylsulfenyl)pyrroles
Thompson, Alison,Garabatos-Perera, Jose R.,Gillis, H. Martin
, p. 676 - 681 (2008/12/21)
The asymmetric oxidation of prochiral 2-(arylsulfenyl)pyrroles has been investigated. A marked electronic effect within the substrate significantly influenced the degree of enantioselectivitv obtained, with very high enantio-selectivity being obtained for
Antidiabetic pyrrolecarboxylic acids
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, (2008/06/13)
Certain pyrrolecarboxylic and pyrroleacetic acid derivatives substituted on the pyrrole ring with thioether groups, acyl groups, phenyl, substituted phenyl, phenoxy, substituted phenoxy, benzyl or halo and optionally substituted on the pyrrole nitrogen with alkyl, and the pharmaceutically acceptable salts thereof, are useful in lowering the blood glucose levels of hyperglycemic animals.
