104615-57-8Relevant academic research and scientific papers
Synthesis, structure, and photoluminescence of 5-phenyl-2-pyridyl-5,6- dihydro[1,2,4]triazolo[1,5-c]quinazolines
Gusev, A. N.,Shulgin, V. F.,Topilova, Z. M.,Meshkova, S. B.
, p. 95 - 98,4 (2020/09/16)
The reactions of salicylaldehyde and benzoic aldehyde with 5-(2-aminophenyl)-3-pyridyl-1?-1,2,4-triazoles were studied. The reaction products are 5-phenyl-2-pyridyl-5,6-dihydro[1,2,4]triazolo[1,5-c]quinazolines. The structures of the synthesized compounds were determined by IR spectroscopy and 1? and 13? NMR spectroscopy. The luminescence properties of solutions and solid samples were studied.
Synthesis and evaluation of adenosine antagonist activity of a series of [1,2,4]triazolo[1,5-c]quinazolines
Balo, Carmen,Lopez, Carmen,Brea, Jose Manuel,Fernandez, Franco,Caamano, Olga
, p. 372 - 375 (2008/02/02)
A series of [1,2,4]triazolo[1,5-c]quinazolines were prepared in satisfactory yields by reaction of some derivatives of 2-aminobenzohydrazide with several hydrochlorides of aromatic amidines, and their binding affinities for the recombinant human adenosine A2A and A2B receptors were determined. None of the new compounds showed noteworthy affinity for these receptors, though a very high affinity for the A2A receptor and, consequently, a high level of A2A/A2B selectivity was revealed for one of the synthesized compounds.
Synthesis and Benzodiazepine Binding Activity of a Series of Novel Triazoloquinazolin-5(6H)-ones
Francis, John E.,Cash, William D.,Barbaz, Beverly S.,Bernard, Patrick S.,Lovell, Richard A.,et al.
, p. 281 - 290 (2007/10/02)
Investigation of tricyclic heterocycles related to the 2-arylpyrazoloquinolin-3(5H)-ones, structures with high affinity for the benzodiazepine (BZ) receptor, led to the synthesis of 2-phenyl-triazoloquinazolin-5(6H)-one, a compound wi
