104615-59-0

Upstream product

• 5584-15-6 5-chloroanthranilic acid hydrazide 
• 74222-83-6 benzamidine hydrochloride hydrate 
• 130408-01-4 ethyl 5-chloroanthranilate hydrochloride 
• 4743-17-3 5-Chloroisatoic anhydride 
• 613-94-5 benzoic acid hydrazide 
• 5922-60-1 2-amino-5-chlorobenzonitrile 
• 100-47-0 benzonitrile 
• 5873-90-5 methyl benzimidate hydrochloride 
• 5202-89-1 4-chlorobenzenesulfonyl chloride 
• 1670-14-0 benzamidine monohydrochloride 
• 153488-32-5 2-benzhydrazide 
• 618-39-3 benzamidin 
• 153488-28-9 3-benzoylamino-6-chloro-4-imino-3,4-dihydroquinazoline 
• 153488-26-7 N-(4-Chloro-2-cyano-phenyl)-formimidic acid ethyl ester 

Downstream Products

• 104615-17-0 5-amino-9-chloro-2-phenyl-<1,2,4>triazolo<1,5-c>quinazoline 
• 153488-61-0 10-chloro-2-phenyl-5H-<1,2,4>-triazolo<1,5-d>benzodiazepin-6(7H)-one 
• 153488-53-0 5-(5-chloro-2-chloroacetylaminophenyl)-3-phenyl-1H-1,2,4-triazole 
• 153488-57-4 9-chloro-5-chloromethyl-2-phenyl-<1,2,4>triazolo<1,5-c>quinazoline 

Relevant academic research and scientific papers

Synthesis of diverse azolo[c]quinazolines by palladium(II)- catalyzed aerobic oxidative insertion of isocyanides

We report the palladium(II)-catalyzed aerobic oxidative coupling of isocyanides with various (2-aminophenyl)azoles using air as the stoichiometric oxidant. A diverse range of medicinally valuable azolo[c]quinazolines was obtained by this new approach.

Synthesis and evaluation of adenosine antagonist activity of a series of [1,2,4]triazolo[1,5-c]quinazolines

A series of [1,2,4]triazolo[1,5-c]quinazolines were prepared in satisfactory yields by reaction of some derivatives of 2-aminobenzohydrazide with several hydrochlorides of aromatic amidines, and their binding affinities for the recombinant human adenosine A2A and A2B receptors were determined. None of the new compounds showed noteworthy affinity for these receptors, though a very high affinity for the A2A receptor and, consequently, a high level of A2A/A2B selectivity was revealed for one of the synthesized compounds.

Halogen substituted imidazol[1,5-A][1,2,4]triazolo[1,5-D][1,4]benzodiazepine derivatives

The invention relates to halogen substituted imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine derivatives of formula I wherein R1, R2, R3, R4 and n are as defined in the specification and to pharmaceutica

Substituted imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine derivatives

The present invention is concerned with a method of treating a disease selected from the group consisting of cognitive disorders, anxiety, Alzheimer's disease, and schizophrenia comprising administering a therapeutically effective amount of a substituted

Synthesis of Triazoloquinazoline and Triazolo-1,4-benzodiazepine Derivatives

Some triazoloquinazolin-5(6H)-ones 7, the corresponding isomers triazoloquinazolin-5(6H)-ones and the 5-amino derivatives 8,9 and 11 have been synthesized starting from the acylamidrazones 5.The preparation of 5H-triazol

Synthesis and Benzodiazepine Binding Activity of a Series of Novel Triazoloquinazolin-5(6H)-ones

Investigation of tricyclic heterocycles related to the 2-arylpyrazoloquinolin-3(5H)-ones, structures with high affinity for the benzodiazepine (BZ) receptor, led to the synthesis of 2-phenyl-triazoloquinazolin-5(6H)-one, a compound wi

A CONVENIENT SYNTHESIS OF 3,5-DISUBSTITUED-1,2,4-TRIAZOLES

The condensation of an acyl hydrazide and an amidine to afford an acylamidrazone, followed by thermal cyclization, provides a convenient method for preparing 3,5-disubstitued-1,2,4-triazoles in high yields.