1046486-34-3Relevant academic research and scientific papers
A comparative study on the experimentally derived electron densities of three protease inhibitor model compounds
Grabowsky, Simon,Pfeuffer, Thomas,Morgenroth, Wolfgang,Paulmann, Carsten,Schirmeister, Tanja,Luger, Peter
body text, p. 2295 - 2307 (2009/02/02)
In order to contribute to a rational design of optimised protease inhibitors which can covalently block the nucleophilic amino acids of the proteases' active sites, we have chosen three model compounds (aziridine l, oxirane 2 and acceptor-substituted olef
