104655-84-7

Basic information

• Product Name: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[tetrakis(1-methylethyl)phosphorodiamidite]
• Synonyms: 5'-O-(4,4'-dimethoxytrityl)thymidine 3'-(N,N,N',N'-tetraisopropyl)phosphorodiamidite;5'-O-(Di-p-methoxytrityl)thymidin-3'-yl-N,N,N',N'-tetraisopropylphosphordiamidite;5‘-O-dimethoxytrityl-2’-deoxyribothymidine 3‘-O-phosphorodiamidite;5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl N,N,N',N'-tetraisopropylphosphorodiamidite;thymidine
• CAS NO: 104655-84-7
• Molecular Formula: C43H59N4O7P
• Molecular Weight: 774.938
• Mol File: 104655-84-7.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[tetrakis(1-methylethyl)phosphorodiamidite](CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[tetrakis(1-methylethyl)phosphorodiamidite](104655-84-7)
• EPA Substance Registry System: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[tetrakis(1-methylethyl)phosphorodiamidite](104655-84-7)

Safety Data

• Hazardous Substances Data: 104655-84-7(Hazardous Substances Data)

Upstream product

• 56183-63-2 bis(diisopropylamino)chlorophosphine 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 50-89-5 thymidine 
• 108-18-9 diisopropylamine 
• 93696-28-7 bis(N,N-diisopropylamino)chlorophosphine 

Downstream Products

• 118149-23-8 O-<5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl> O-(3'-O-acetylthymidin-5'-yl) N,N-diisopropylphosphoramidite 
• 104655-86-9 C₅₄H₆₂N₅O₁₃P 
• 200502-04-1 2,2-dimethyl-thiopropionic acid S-(2-{[2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxy]-diisopropylamino-phosphanyloxy}-ethyl) ester 
• 291299-79-1 5'-O-(4,4'-dimethoxytrityl)-3'-O-(N,N-diisopropylamino)-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethoxy]phosphinyl-2'-deoxythymidine 
• 154664-90-1 5'-O-(4,4'-dimethoxytrityl)thymidine 3'-O-[2-(trimethylsilyl)ethyl] diisopropylphosphoramidite 
• 1173883-18-5 5'-O-dimethoxytritylthymidine 3'-O-[(5-nitro-2-furyl)methyl-N,N-diisopropylphosphoramidite] 
• 1173883-19-6 5'-O-dimethoxytritylthymidine 3'-O-[(5-nitro-2-thienyl)methyl-N,N-diisopropylphosphoramidite] 
• 84416-85-3 [5'-O-(4,4'-dimethoxytrityl)thymidine-3'-yl]-(N,N'-diisopropyl)methylphosphoramidite 
• 133729-08-5 C₅₀H₅₂ClN₄O₁₃PS 
• 118149-24-9 O-<5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl> O-(3'-O-acetylthymidin-5'-yl) hydrogenphosphonothioate 

Relevant articles and documents

SOLID-PHASE SYNTHESIS OF MODIFIED OLIGODEOXYRIBONUCLEOTIDES WITH AN ACRIDINE DERIVATIVE OR A THIOPHOSPHATE GROUP AT THEIR 3' END

Use of a derivatized support involving the 2,2'-diethyldithio-group 7 allows the automated synthesis of oligodeoxyribonucleotide bearing acridine derivative (via nucleoside -3'-acridinylphosphoramidite 3) or 3'phosphorothioate group (including the sulfuri

An improved method for the preparation of 4-cyano-2-butenyl- deoxyribonucleosidephosphoramidites

An improved alternative synthesis of 4-cyano-2-butenyldeoxy nucleosidephosphoramidites in >100g quantities is described via reaction of the phosphordiamidites with 4-cyano-2-buten-1-ol.

Compound, fluorescence-labeled-introducing agent, and introducing fluorescent labeling method (by machine translation)

[Problem] no fluorescence whereas the extracellular, intracellular fluorescence of fluorescently labeled compound is incorporated, and such fluorescent labeling for introducing fluorescent labeling agent is introduced. (1) A compound represented by general formula [a] is used. In the general formula (1), the A, biological material or derivatives thereof may be incorporated into the cell through a cell membrane structure 1 comprises a divalent group, the FL, fluorescent light having a fluorescent unit which exhibits cyclic backbone nitrogen atom, L is, a monovalent group FL A coupling 2, the X, a single bond or O - (=O) a - C, wavy lines represent bonds, the nitrogen atom is bound to a FL included, the Ar, para or ortho position of the aromatic ring which has a valence bond 2, R is, nitro or - S e S a-R1 And, R1 Is, a monovalent group, n the, an integer of 1 - 3. [Drawing] no (by machine translation)

PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES

Novel nucleoside phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide and synthetic processes for making the same are disclosed. Furthermore, oligomeri