An improved method for the preparation of 4-cyano-2-butenyl- deoxyribonucleosidephosphoramidites

Article abstract of DOI:10.1080/07328319908044671

An improved alternative synthesis of 4-cyano-2-butenyldeoxy nucleosidephosphoramidites in >100g quantities is described via reaction of the phosphordiamidites with 4-cyano-2-buten-1-ol.

Full text of DOI:10.1080/07328319908044671

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Nucleosides and Nucleotides
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An Improved Method for the
Preparation of 4-Cyano-2-butenyl-
deoxyribonucleosidephosphoramidites
a
a
G. Duckworth & J. Ackroyd
a
Cruachem Ltd Todd Campus, West of Scotland Science Park , Acre
Road, Glasgow, Scotland , G20 OUA
Published online: 04 Oct 2006.
To cite this article: G. Duckworth & J. Ackroyd (1999) An Improved Method for the Preparation of
4
1
-Cyano-2-butenyl-deoxyribonucleosidephosphoramidites, Nucleosides and Nucleotides, 18:6-7,
227-1229, DOI: 10.1080/07328319908044671
To link to this article: http://dx.doi.org/10.1080/07328319908044671
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