104655-93-8

Basic information

• Product Name: 5'-O-(4,4'-dimethoxytrityl)thymidine-3'-yl S-phenyl phosphorothioate trimethylsilyl ester
• CAS NO: 104655-93-8
• Molecular Weight: 788.931
• Mol File: 104655-93-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-(4,4'-dimethoxytrityl)thymidine-3'-yl S-phenyl phosphorothioate trimethylsilyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4,4'-dimethoxytrityl)thymidine-3'-yl S-phenyl phosphorothioate trimethylsilyl ester(104655-93-8)
• EPA Substance Registry System: 5'-O-(4,4'-dimethoxytrityl)thymidine-3'-yl S-phenyl phosphorothioate trimethylsilyl ester(104655-93-8)

Safety Data

• Hazardous Substances Data: 104655-93-8(Hazardous Substances Data)

Upstream product

• 182245-71-2 C₃₇H₄₉N₂O₉PSi₂ 
• 882-33-7 diphenyldisulfane 
• 75-77-4 chloro-trimethyl-silane 

Relevant articles and documents

Nucleoside Phosphonates: Part 7. Studies on the Oxidation of Nucleoside Phosphonate Esters

Oxidation of phosphonate mono- and di-esters with various oxidizing agents including diaryl disulphides, hexacloroacetone, and iodine, has been investigated under various reaction conditions.The most efficient oxidation procedure consists of treatment of phosphonate esters with iodine in pyridine-water.When the phosphonate esters were presilylated by treatment with trimethylsilyl chloride, the subsequent oxidation with aqueous iodine was faster. (31)P N.m.r. spectroscopic studies have enabled us to propose the most likely pathway for the majority of the oxidations.