104672-22-2Relevant academic research and scientific papers
A new boronic-acid based strategy to synthesize 4(5)-(het)aryl-1H-imidazoles
Primas, Nicolas,Mahatsekake, Clément,Bouillon, Alexandre,Lancelot, Jean-Charles,Oliveira Santos, Jana Sopkovà-de,Lohier, Jean-Fran?ois,Rault, Sylvain
, p. 4596 - 4601 (2008/09/20)
This paper describes the synthesis of a new N-THP protected 5-(1H)-imidazolyl boronic acid pinacol ester and its use in Suzuki cross-coupling reactions with a wide range of (het)aryl halides to provide 4(5)-(het)aryl-1H-imidazoles.
CARBENIC REACTIONS OF 4-DIAZO-4H-IMIDAZOLE WITH BENZENE DERIVATIVES
Amick, T. J.,Shechter, H.
, p. 901 - 904 (2007/10/02)
The electrophilic behavior of 4H-imidazolylidene is greatly modified by coordinating groups in benzene derivatives undergoing substitution.
Chlorinated imidazole derivatives and a process for preparing them
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, (2008/06/13)
Imidazole derivatives, useful as intermediates for making herbicides, having the formula STR1 wherein X is chlorine, lower alkyl mono- or polysubstituted by chlorine, or aryl which is optionally mono- or polysubstituted by halogen and/or lower alkyl and R1 and R2 are identical or different and are chlorine or phenyl optionally substituted by halogen and/or lower alkyl. The imidazole derivatives are prepared by converting an imidazole derivative having the formula STR2 wherein X' is hydrogen, lower alkyl or aryl optionally substituted by halogen atom and/or lower alkyl and R'1 and R'2 are identical and represent hydrogen and/or phenyl optionally substituted by halogen and/or lower alkyl By means of hydrogen chloride, in the absence of water, into the corresponding hydrochloride, subsequently reacting with hydrochloride with an excess of chlorine at elevated temperature.
