104672-24-4Relevant academic research and scientific papers
Structure-activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain
Yang, Shu-Wei,Smotryski, Jennifer,Matasi, Julius,Ho, Ginny,Tulshian, Deen,Greenlee, William J.,Brusa, Rossella,Beltramo, Massimiliano,Cox, Kathleen
scheme or table, p. 182 - 185 (2011/02/27)
A series of 2,4-diphenyl-1H-imidazole analogs have been synthesized and displayed potent human CB2 agonist activity. Many of these analogs showed high functional selectivity over human CB1 receptors. The syntheses, structure-activity relationships, and selected pharmacokinetic data of these analogs are described.
P70 S6 KINASE INHIBITORS
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Page/Page column 40, (2009/01/20)
The present invention provides p70 S6 kinase inhibitors of the formula: pharmaceutical formulations comprising them, and methods for their use.
CARBENIC REACTIONS OF 4-DIAZO-4H-IMIDAZOLE WITH BENZENE DERIVATIVES
Amick, T. J.,Shechter, H.
, p. 901 - 904 (2007/10/02)
The electrophilic behavior of 4H-imidazolylidene is greatly modified by coordinating groups in benzene derivatives undergoing substitution.
