1046791-05-2Relevant academic research and scientific papers
Studies of Catalyst-Controlled Regioselective Acetalization and Its Application to Single-Pot Synthesis of Differentially Protected Saccharides
Wang, Sibin,Zhelavskyi, Oleksii,Lee, Jeonghyo,Argüelles, Alonso J.,Khomutnyk, Yaroslav Ya.,Mensah, Enoch,Guo, Hao,Hourani, Rami,Zimmerman, Paul M.,Nagorny, Pavel
, p. 18592 - 18604 (2021/11/16)
This article describes studies on the regioselective acetal protection of monosaccharide-based diols using chiral phosphoric acids (CPAs) and their immobilized polymeric variants, (R)-Ad-TRIP-PS and (S)-SPINOL-PS, as the catalysts. These catalyst-controll
Synthesis of a GM3 ganglioside analogue carrying a phytoceramide moiety by intramolecular glycosylation as a key step
Fujikawa, Kohki,Imamura, Akihiro,Ishida, Hideharu,Kiso, Makoto
experimental part, p. 2729 - 2734 (2009/04/11)
A novel analogue of ganglioside GM3, in which sphingosine was replaced with a phytosphingosine moiety, was synthesized by intramolecular glycosylation as a key step. Glucose, a reducing terminal of the saccharide, and phytoceramide were first tethered by succinic acid and the derivative used for the subsequent glycosidic bond formation. The obtained glycosyl phytoceramide was further glycosylated with the sialyl galactose residue to afford a fully protected GM3 derivative, which was converted into the desired, final compound by using conventional deprotection procedures.
