104749-69-1Relevant academic research and scientific papers
N-CYANO-N'-ALKYLIMIDAZOLIUM YLIDS AS NOVEL INTERMEDIATES TO 2-CYANOIMIDAZOLES
McCarthy, James R.,Matthews, Donald P.,Whitten, Jeffrey P.
, p. 6273 - 6276 (1985)
N-Substituted imidazoles were readily converted to 2-cyanoimidazoles by treatment with cyanogen chloride followed by triethylamine.The utilization of the SEM protecting group provided a facile entry to N-unsubstituted 2-cyanoimidazoles.
Cyanogen Bromide-Dimethylaminopyridine (CAP): A Convenient Source of Positive Cyanide for the Synthesis of 2-Cyanoimidazoles
Whitten, Jeffrey P.,McCarthy, James R.,Matthews, Donald P.
, p. 470 - 472 (1988)
Dimethylaminopyridine activates cyanogen bromide towards C-C bond formation by forming 1-cyano-4-dimethylaminopyridinium bromide.The latter serves as a convenient reagent for the synthesis of 2-cyanoimidazoles.
2,2'-bi-1H-imidazoles
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, (2008/06/13)
This invention relates to novel derivatives of 2,2'-bi-1H-imidazoles, to the processes and intermediates used in their preparation, to their ability to exert the pharmacologic effects of lowering high blood pressure and of increasing heart contractile force and to their use as chemotherpauetic agents useful in treating cardiac insufficiency and hypertension.
