Cyanogen Bromide-Dimethylaminopyridine (CAP): A Convenient Source of Positive Cyanide for the Synthesis of 2-Cyanoimidazoles

DOI: 10.1055/s-1988-27609

Source and publish data:

Synthesis p. 470 - 472 (1988)

Update date:2022-08-11

Topics:

Authors:

Whitten, Jeffrey P.

McCarthy, James R.

Matthews, Donald P.

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Article abstract of DOI:10.1055/s-1988-27609

Dimethylaminopyridine activates cyanogen bromide towards C-C bond formation by forming 1-cyano-4-dimethylaminopyridinium bromide.The latter serves as a convenient reagent for the synthesis of 2-cyanoimidazoles.

Full text of DOI:10.1055/s-1988-27609

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