1047646-62-7Relevant articles and documents
Chiral amine thiourea-promoted enantioselective domino Michael-aldol reactions between 2-mercaptobenzaldehydes and maleimides
Zu, Liansuo,Xie, Hexin,Li, Hao,Wang, Jian,Jiang, Wei,Wang, Wei
, p. 1882 - 1886 (2008/09/17)
An organocatalytic, enantioselective domino Michael-aldol reaction of 2-mercaptobenz-aldehydes with maleimides has been developed. The process, catalyzed by a bifunctional chiral amine thiourea via a hydrogen-bonding mediated activation mechanism using as