1047671-76-0

Basic information

• Product Name: (3R)-1-methyl-3-{[(5-phenyl-1,3-thiazol-4-yl)carbamoyl]oxy}-1-azoniabicyclo[2.2.2]octane iodide
• Synonyms: (3R)-1-methyl-3-{[(5-phenyl-1,3-thiazol-4-yl)carbamoyl]oxy}-1-azoniabicyclo[2.2.2]octane iodide
• CAS NO: 1047671-76-0
• Molecular Weight: 471.362
• Mol File: 1047671-76-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R)-1-methyl-3-{[(5-phenyl-1,3-thiazol-4-yl)carbamoyl]oxy}-1-azoniabicyclo[2.2.2]octane iodide(CAS DataBase Reference)
• NIST Chemistry Reference: (3R)-1-methyl-3-{[(5-phenyl-1,3-thiazol-4-yl)carbamoyl]oxy}-1-azoniabicyclo[2.2.2]octane iodide(1047671-76-0)
• EPA Substance Registry System: (3R)-1-methyl-3-{[(5-phenyl-1,3-thiazol-4-yl)carbamoyl]oxy}-1-azoniabicyclo[2.2.2]octane iodide(1047671-76-0)

Safety Data

• Hazardous Substances Data: 1047671-76-0(Hazardous Substances Data)

Upstream product

• 98-80-6 phenylboronic acid 
• 13743-14-1 5-phenyl-1,3-thiazole-4-carboxylic acid 
• 61323-28-2 ethyl-5‐phenyl‐1,3‐thiazole‐4‐carboxylate 
• 1047672-88-7 (3R)-1-azabicyclo[2.2.2]oct-3-yl (5-phenyl-1,3-thiazol-4-yl)carbamate hydrochloride 
• 74-88-4 methyl iodide 

Relevant articles and documents

Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists

Herein, we describe the synthesis and pharmacological profiles of novel quinuclidinyl heteroarylcarbamate derivatives. Among them, the quinuclidin-4-yl thiazolylcarbamate derivative ASP9133 was identified as a promising long-acting muscarinic antagonist (LAMA) showing more selective inhibition of bronchoconstriction against salivation and more rapid onset of action in a rat model than tiotropium bromide.