1047683-68-0Relevant academic research and scientific papers
Design and synthesis of (E)-1-((3-ethyl-2,4,4-trimethylcyclohex-2- enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1-enyl) ethanol
Das, Bhaskar C.,Mahalingam, Sakkarapalayam M.,Evans, Todd,Kabalka, George W.,Anguiano,Hema
scheme or table, p. 2133 - 2135 (2009/09/05)
A novel strategy for synthesizing (E)-1-((3-ethyl-2,4,4-trimethylcyclohex- 2-enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1- enyl)ethanol 3 has been developed; the allylic alcohol 3 was treated with PPh3·HBr in methan
Design, synthesis of novel peptidomimetic derivatives of 4-HPR for rhabdoid tumors
Das, Bhaskar C.,Smith, Melissa E.,Kalpana, Ganjam V.
scheme or table, p. 4177 - 4180 (2009/05/07)
Rhabdoid tumors (RTs) are an extremely aggressive pediatric malignancy that results from loss of the INI1/hSNF5 tumor suppressor gene. Loss of INI1 results in aberrant expression of Cyclin D1, which supports rhabdoid tumorigenesis and survival. 4-HPR, a s
Design and synthesis of (E)-4-((3-ethyl-2,4,4-trimethylcyclohex-2-enylidene)methyl)benzoic acid
Das, Bhaskar C.,Kabalka, George W.
, p. 4695 - 4696 (2008/09/21)
(E)-4-((3-Ethyl-2,4,4-trimethylcyclohex-2-enylidene)methyl)benzoic acid, 6, was synthesized in 87% starting from β-cyclocitral. The target compound 6 was synthesized starting from 1 via a Grignard reaction to form alcohol 2. Compound 2 was converted to Wi
