104775-66-8

Basic information

• Product Name: 2-amino-4-chloro-N-methylbenzamide(SALTDATA: FREE)
• Synonyms: 2-amino-4-chloro-N-methylbenzamide(SALTDATA: FREE);Benzamide, 2-amino-4-chloro-N-methyl-
• CAS NO: 104775-66-8
• Molecular Formula: C8H9ClN2O
• Molecular Weight: 184.62286
• Mol File: 104775-66-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 353.007°C at 760 mmHg
• Flash Point: 167.293°C
• Appearance: /
• Density: 1.282g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: 2-amino-4-chloro-N-methylbenzamide(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-chloro-N-methylbenzamide(SALTDATA: FREE)(104775-66-8)
• EPA Substance Registry System: 2-amino-4-chloro-N-methylbenzamide(SALTDATA: FREE)(104775-66-8)

Safety Data

• Hazardous Substances Data: 104775-66-8(Hazardous Substances Data)

Usage

General Description

2-amino-4-chloro-N-methylbenzamide is a chemical compound with the molecular formula C8H9ClN2O. It is an organic compound that contains an amine, chloro, and benzamide functional group. 2-amino-4-chloro-N-methylbenzamide(SALTDATA: FREE) is known for its free state of SALTDATA, which means it is not bound to a salt form. It is commonly used as an intermediate in the synthesis of pharmaceutical drugs and other organic compounds. Additionally, it has potential applications in the field of medicinal chemistry and drug discovery due to its structural properties.

InChI:InChI=1/C8H9ClN2O/c1-11-8(12)6-3-2-5(9)4-7(6)10/h2-4H,10H2,1H3,(H,11,12)

Upstream product

• 89-77-0 2-Amino-4-chlorobenzoic acid 
• 1397833-65-6 (2-amino-4-chlorophenyl) (benzotriazole-1-yl)methanone 
• 74-89-5 methylamine 
• 593-51-1 methylamine hydrochloride 

Downstream Products

• 1612771-93-3 7-chloro-2-(4-chloro-3-nitrophenyl)-3-methyl-2,3-dihydroquinazolin-4(1H)-one 
• 1612771-92-2 7-chloro-3-methyl-2-(4-(trifluoromethoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one 
• 1612771-91-1 7-chloro-2-(2,4-dimethoxyphenyl)-3-methyl-2,3-dihydroquinazolin-4(1H)-one 
• 1612771-90-0 7-chloro-2-(2-chloro-5-nitrophenyl)-3-methyl-2,3-dihydroquinazolin-4(1H)-one 
• 1542270-75-6 7-chloro-2-(2-chloro-6-fluorophenyl)-3-methyl-2,3-dihydroquinazolin-4(1H)-one 
• 1612771-94-4 7-chloro-2-(3-methoxyphenyl)-3-methyl-2,3-dihydroquinazolin-4(1H)-one 
• 1612771-85-3 7-chloro-3-methyl-2-phenyl-2,3-dihydroquinazolin-4(1H)-one 

Relevant articles and documents

Palladium-Catalyzed Oxidative Three-Component Coupling of Anthranilamides with Isocyanides and Arylboronic Acids: Access to 2,3-Disubstituted Quinazolinones

A novel palladium-catalyzed oxidative three-component coupling of easily accessible N-substituted anthranilamides with isocyanides and arylboronic acids is achieved. This protocol offers an alternative approach toward 2,3-disubstituted quinazolinones with a wide substrate scope and good functional group tolerance.

A new protocol for the synthesis of primary, secondary and tertiary anthranilamides utilizing N-(2-aminoarylacyl)benzotriazoles

A convenient route for efficient conversion of unprotected anthranilic acids into the corresponding N-(2-aminoarylacyl)benzotrazoles is described. N-(2-Aminoarylacyl)-benzotrazoles have been successfully used to synthesize primary, secondary and tertiary anthranilamides in high yields (71-96%). ARKAT-USA, Inc.

PYRIDINE COMPOUNDS

The present invention relates to compounds that inhibit of focal adhesion kinase function, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment in warm-blooded animals such as humans of diseases such as cancer.