104778-58-7 Usage
Description
1-benzyl-3-(chloromethyl)piperidine(SALTDATA: HCl) is a chemical compound characterized by a piperidine structure with a benzyl group attached and a chloromethyl group at the 3-position. The HCl salt form enhances its stability and solubility, making it a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals. Its high reactivity due to the chloromethyl group allows it to participate in a variety of chemical reactions, contributing to its utility in the development of new drugs and medications.
Uses
Used in Pharmaceutical Industry:
1-benzyl-3-(chloromethyl)piperidine(SALTDATA: HCl) is used as a chemical intermediate for the synthesis of various pharmaceuticals and agrochemicals. Its high reactivity and the presence of the chloromethyl group enable it to participate in multiple chemical reactions, facilitating the creation of new drugs and medications.
The specific applications and reasons for its use in the pharmaceutical industry are not provided in the materials. However, given its role as a chemical intermediate, it is likely used in the synthesis of compounds with therapeutic properties or as a precursor in the production of active pharmaceutical ingredients.
Check Digit Verification of cas no
The CAS Registry Mumber 104778-58-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,7,7 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 104778-58:
(8*1)+(7*0)+(6*4)+(5*7)+(4*7)+(3*8)+(2*5)+(1*8)=137
137 % 10 = 7
So 104778-58-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H18ClN/c14-9-13-7-4-8-15(11-13)10-12-5-2-1-3-6-12/h1-3,5-6,13H,4,7-11H2
104778-58-7Relevant articles and documents
3-piperidine Derivatives. Synthesis and Antidepressant Activity
Balsamo, A.,Giorgi, I.,Lapucci, A.,Lucacchini, A.,Macchia, B.,et al.
, p. 222 - 225 (2007/10/02)
The 3-piperidine derivatives 3-5 were synthesized and screened as potential antidepressant agents by the reserpine interaction test in mice and the evaluation of reuptake inhibition of biogenic amines in pig brain synaptosomal fractions.In addition, their anticonvulsant activity, tested by pentylenetetrazole antagonism, and approximate acute toxicity were evaluated.In vivo and in vitro tests showed that compounds 3 and 5 possess a biological activity comparable to that of the antidepressant drug viloxazine (2).
