104778-76-9Relevant academic research and scientific papers
SN2′ selective alkylation of allylic chlorides and mesylates with RZnX reagents generated from Grignard reagents, zinc chloride, lithium chloride, and Cu(II)-salts
Fujii, Nobutaka,Nakai, Kazuo,Habashita, Hiromu,Yoshizawa, Hidenori,Ibuka, Toshiro,Garrido, Fabrice,Mann, Andre,Chounan, Yukiyasu,Yamamoto, Yoshinori
, p. 4227 - 4230 (2007/10/02)
Treatment of RMgX (1 equiv. R = alkyl; X = Cl, Br) with ZnCl2 (1 equiv.) in a mixed solvent of THF and Et2O leads to a highly turbid white suspension. Addition of LiCl (1～2 equiv.) solubilizes the insoluble species to yield a colorless clear solution. Addition of a catalytic amount of a Cu(II)-.
Very High Chemoselective, Regioselective, and E-Stereoselective 1,3-Chirality Transfer Involving Reaction of Acyclic (E)- and (Z)-γ-Mesyloxy α,β-Enoates and Organocyanocopper-Trifluoroborane Reagents. Efficient Synthetic Routes to Functionalized Chiral α-
Ibuka, Toshiro,Tanaka, Miwa,Nishii, Shinji,Yamamoto, Yoshinori
, p. 4864 - 4872 (2007/10/02)
Reaction of γ-mesyloxy (E)- or (Z)-α,β-enoates with Me2Cu(CN)Li2*BF3 (prepared from MeLi-LiI in ether), MeCu(CN)Li*BF3 (prepared from MeLi-LiBr in ether), and RCu(CN)Li*BF3 (R = Et, n-Pr, n-Bu) in tetrahydrofuran or mixed solvents involving tetrahydrofura
