10480-27-0 Usage
Uses
Used in Pharmaceutical Industry:
N-(3-Chlorophenyl)-3-nitrobenzenemethanimine is used as an intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
N-(3-Chlorophenyl)-3-nitrobenzenemethanimine is used as an intermediate in the synthesis of agrochemicals, specifically as an insecticide and acaricide. Its chemical properties make it effective in controlling pests and mites in agricultural settings.
Safety Precautions:
Due to its toxic and harmful effects, it is crucial to handle N-(3-Chlorophenyl)-3-nitrobenzenemethanimine with care. Ingestion, inhalation, or skin absorption can lead to adverse health effects. Proper safety measures, such as wearing protective gear and following handling guidelines, should be strictly adhered to during its use in both pharmaceutical and agrochemical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 10480-27-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,8 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10480-27:
(7*1)+(6*0)+(5*4)+(4*8)+(3*0)+(2*2)+(1*7)=70
70 % 10 = 0
So 10480-27-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H9ClN2O2/c14-11-4-2-5-12(8-11)15-9-10-3-1-6-13(7-10)16(17)18/h1-9H/b15-9+
10480-27-0Relevant academic research and scientific papers
Mechanochemical milling promoted solvent-free imino Diels-Alder reaction catalyzed by FeCl3: Diastereoselective synthesis of cis-2,4-diphenyl-1,2,3,4-tetrahydroquinolines
Tan, Ya-Jun,Zhang, Ze,Wang, Fang-Jian,Wu, Hao-Hao,Li, Qing-Hai
, p. 35635 - 35638 (2014/11/07)
Under mechanochemical ball-milling at room temperature, FeCl3 promoted Diels-Alder cycloaddition of styrene with in situ generated N-aryl aldimines in the absence of any solvent afforded exclusively cis-2,4-diphenyltetrahydroquinolines in good to excellent yields within 90 minutes. The isolation work up just involves washing the resulting reaction mixture with water and recrystallization from EtOH-H2O. The advantages of high diastereoselectivity, short reaction time, free use of organic solvent, low cost, employment of cheap, easily available and nontoxic catalyst, and simple work-up procedure make this protocol a very efficient and green alternative to traditional methods for constructing these kinds of heterocyclic skeletons.
