10480-32-7

Basic information

• Product Name: 4-chloro-N-[(E)-(4-chlorophenyl)methylidene]aniline
• Synonyms: Aniline, p-chloro-N- (p-chlorobenzylidene)-; p-chlorobenzylidene-(4-chlorophenyl)-amine; p-Chlorobenzylidene-p-chloroaniline
• CAS NO: 10480-32-7
• Molecular Formula: C₁₃H₉Cl₂N
• Molecular Weight: 250.1233
• Mol File: 10480-32-7.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 367.5°C at 760 mmHg
• Flash Point: 176.1°C
• Density: 1.2g/cm³
• Vapor Pressure: 2.87E-05mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: 4-chloro-N-[(E)-(4-chlorophenyl)methylidene]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-N-[(E)-(4-chlorophenyl)methylidene]aniline(10480-32-7)
• EPA Substance Registry System: 4-chloro-N-[(E)-(4-chlorophenyl)methylidene]aniline(10480-32-7)

Safety Data

• Hazardous Substances Data: 10480-32-7(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 106-47-8 4-chloro-aniline 
• 873-76-7 para-Chlorobenzyl alcohol 
• 614-30-2 N-methyl-N-phenyl-benzenemethanamine 
• 758640-21-0 N-Benzylaniline 
• 13159-74-5 4-chloro-N-(4-chlorobenzyl)aniline 

Downstream Products

• 13159-74-5 4-chloro-N-(4-chlorobenzyl)aniline 
• 38550-06-0 2-[4-(4-chloro-styryl)-phenyl]-2H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2,3]triazole 
• 20841-15-0 2,3,3-tributyl-1,5-bis-(4-chloro-phenyl)-4-phenyl-[1,4,2]diazaborolidine 
• 61973-89-5 2,6-Bis-[(E)-2-(4-chloro-phenyl)-vinyl]-pyridine 
• 103589-01-1 2,3-dihydro-2-(4-chlorophenyl)-3-(4-chlorophenyl)benzoquinazolin-4(1H)-one 
• 75158-93-9 C₃₃H₂₄Cl₂N₂O₂S₂ 
• 85495-08-5 1,4-Bis-(4-chloro-phenyl)-3-(toluene-4-sulfonyl)-azetidin-2-one 
• 88252-47-5 2-[(2R,3R)-1,2-Bis-(4-chloro-phenyl)-4-oxo-azetidin-3-yl]-isoindole-1,3-dione 
• 102912-65-2 2-[(Z)-2-(4-Chloro-phenyl)-vinyl]-naphtho[1,2-d]thiazole 
• 81017-17-6 1,4-Bis-(4-chloro-phenyl)-3-phenoxy-azetidin-2-one 
• 139484-10-9 2-((4-chlorophenyl)(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)methyl)-3-hydroxy-5,5-dimethylcyclohex-2-enone 
• 15782-02-2 9-(4-chlorophenyl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydroxanthene-1,8-dione 
• 1191105-42-6 4-chloro-N-(5-chloro-2,3-diphenyl-1H-inden-1-ylidene)benzenamine 
• 1263433-07-3 C₁₉H₁₈Cl₂N₂O 

Relevant articles and documents

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Nanomagnetic catalysis (Fe3O4@S–TiO2): a novel magnetically nano catalyst for the synthesis of new highly substituted tetrahydropyridine derivatives under solvent-free conditions

A novel nanomagnetic catalyst (Fe3O4@S–TiO2) was prepared by the hydrothermal method. At the first, Fe3O4 nanoparticles were synthesized, then iron oxide nanoparticles (IONPs) were dispersed in ethano

Diethylsilane as a Powerful Reagent in Au Nanoparticle-Catalyzed Reductive Transformations

Diethylsilane (Et2SiH2), a simple and readily available dihydrosilane, that exhibits superior reactivity, as compared to monohydrosilanes, in a series of reductive transformations catalyzed by recyclable and reusable Au nanoparticles (1 mol-%) supported on TiO2. It reduces aldehydes or ketones almost instantaneously at ambient conditions. It can be used in a one pot rapid reductive amination procedure, in which premixing of aldehyde and amine is required prior to the addition of the reducing agent and the catalyst, even in a protic solvent. An unprecedented method for the synthesis of N-arylisoindolines is also shown in the reductive amination between o-phthalaldehyde and anilines. In this transformation, it is proposed that the intermediate N,2-diphenylisoindolin-1-imines are reduced stepwise to the isoindolines. Finally, Et2SiH2 readily reduces amides into amines in excellent yields and shorter reaction times relative to previously known analogous nano Au(0)-catalyzed protocols.

Visible light photocatalytic aerobic oxidative synthesis of imines from alcohols and amines on dye-sensitized TiO2

A general visible light photocatalytic protocol for the synthesis of imines via a two-step one-pot route on alizarin red S (ARS)-sensitized TiO2 was uncovered. This efficient synthesis protocol involves one step of the highly selective formation of aldehydes from the oxidation of alcohols with O2 on ARS-sensitized TiO2 photocatalyst, and a subsequent step of condensation of newly formed aldehydes with various amines on TiO2 to afford imines in one pot. Anatase TiO2 provides a versatile platform for catalytic amounts of ARS (0.67 mol%) to facilitate the electron transfer from dye traversing its conduction band to O2 under green LED irradiation. Moreover, the Lewis acid sites of TiO2 can promote the formation of imines from aldehydes and amines in very high isolated yields. We took advantage of both the photocatalytic and catalytic properties of TiO2 to significantly expand the scope of imines. Our work suggests that the synthetic applications of TiO2 photocatalysis can be achievable under mild conditions by exploring the excellent functionalities of TiO2.