104818-20-4

Upstream product

• 104748-19-8 3-perfluorooctylbenzenesulfonic acid 
• 591-50-4 iodobenzene 
• 507-63-1 1-iodoheptadecafluorooctane 
• 87405-83-2 (heptadecafluorooctyl)benzene 

Downstream Products

• 335003-85-5 [3-(perfluorooctyl)phenyl]sulfonamide 
• 882853-82-9 C₂₂H₉F₁₇INO₂S 
• 335004-46-1 N-[(E)-4-bromo-2-butenyl]-N-(tert-butyloxycarbonyl)[3-(perfluorooctyl)phenyl]sulfonamide 
• 335004-16-5 N-(tert-butyloxycarbonyl)[3-(perfluorooctyl)phenyl]sulfonamide 
• 882853-73-8 C₂₇H₁₃BrF₁₇N₃O₃S 
• 882853-61-4 C₃₀H₁₅BrF₁₇NO₆S 
• 882853-60-3 C₂₈H₂₁BF₁₇NO₄S 
• 958250-28-7 1-(3-(perfluorooctyl)benzenesulfonyl)indole 

Relevant academic research and scientific papers

COMPOUNDS AND PROCESSES FOR PRODUCTION OF RADIOPHARMACEUTICALS

The present invention relates to novel perfluorinated precursors for the production of F- 18 labeled radiotracers for Positron Emission Tomography (PET) and processes for radiolabeling and purification using these precursors. The invention also comprises radiopharmaceutical kits using these precursors and processes.

Fluorous synthesis of yuehchukene by α-lithiation of perfluoroalkyl-tagged 1-(arylsulfonyl)indole with mesityllithium

Lithiation chemistry has not been well explored in fluorous synthesis because of the lack of appropriate base-resistant fluorous tags; we recently developed a perfluoroalkylated arylsulfonyl tag for the protection of the indole ring nitrogen atom. Mesityl

Fluorous-tagged indolylboron for the diversity-oriented synthesis of biologically-attractive bisindole derivatives

The diversity-oriented synthesis of bisindole derivatives to construct concise libraries using consecutive cross-coupling reactions and prepare new sulfonamide type fluorous protecting groups is presented. The Royal Society of Chemistry 2006.

Preparation of nitrogen-containing 15-membered triolefinic macrocycles: (E,E,E)-1,6,11-tris(arylsulfonyl)-1,6,11-triazacyclopentadeca-3,8,13-trienes

Three routes to (E,E,E)-1,6,11-tris(arylsulfonyl)-1,6,11-triazacyclopentadeca-3,8,13-trienes are described. Optimization of the preparation of key intermediates has opened the way to efficient synthesis of a broad variety of 15-membered, nitrogen-containing triolefinic macrocycles.

PERFLUOROALKYLBENZENESULFONYL CHLORIDES, PERFLUOROAKYLNAPHTHALENESULFONYL CHLORIDES, AND THEIR METAL SALTS

Meta-perfluoro-n-alkylbenzenesulfonyl chlorides and 1-perfluoro-n-alkylnaphthalene-5-sulfonyl chlorides were synthesized from the corresponding perfluoroalkylaromatics in good yield by the action of chlorosulfonic acid.From the acid chlorides, salts (RSO3M, where M = Li, K, Ba, Zn and Al) were prepared and their TGA curves obtained.With the exception of the aluminum salts, the materials were stable to at least 350 deg C.All salts were essentially insoluble in Cl(CFClCF2)3-4Cl.