10482-83-4Relevant academic research and scientific papers
Asymmetric Cycloisomerization of o-Alkenyl-N-Methylanilines to Indolines by Iridium-Catalyzed C(sp3)?H Addition to Carbon–Carbon Double Bonds
Torigoe, Takeru,Ohmura, Toshimichi,Suginome, Michinori
supporting information, p. 14272 - 14276 (2017/10/23)
Highly enantioselective cycloisomerization of N-methylanilines, bearing o-alkenyl groups, into indolines is established. An iridium catalyst bearing a bidentate chiral diphosphine effectively promotes the intramolecular addition of the C(sp3)?H bond across a carbon–carbon double bond in a highly enantioselective fashion. The reaction gives indolines bearing a quaternary stereogenic carbon center at the 3-position. The reaction mechanism involves rate-determining oxidative addition of the N-methyl C?H bond, followed by intramolecular carboiridation and subsequent reductive elimination.
High-enantioselectivity 1,1-diarylboroalkanes and preparation method thereof
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Paragraph 0084; 0085; 0086; 0087, (2017/07/21)
The invention provides high-enantioselectivity 1,1-diarylboroalkanes and a preparation method thereof, belonging to the technical field of organic synthetic chemistry. The structural general formula of the compounds is disclosed as Formula I. The invention also provides a preparation method of the high-enantioselectivity 1,1-diarylboroalkanes. The method comprises the following steps: carrying out reaction on a copper salt and an alkali under the catalytic action of an alkali to generate a tert-butyl oxy copper intermediate, and reacting with pinacol biborate to generate a copper-boron material, inserting C-C double bonds, and obtaining the hydrogen bononization products under the action of alcohol. The 1,1-diarylboroalkanes have high enantioselectivity; and the high performance liquid chromatography experiment proves that the ee value can reach 90% or above.
Palladium-Catalyzed Coupling of Sulfonylhydrazones with Heteroaromatic 2-Amino-Halides (Barluenga Reaction): Exploring the Electronics of the Sulfonylhydrazone
Tan, Hongyu,Houpis, Ioannis,Liu, Renmao,Wang, Youchu,Chen, Zhilong,Fleming, Matthew J.
supporting information, p. 1044 - 1048 (2015/09/01)
This paper describes a new reactivity of the Pd-catalyzed coupling of 2-amino-3-bromo-aromatic and heteroaromatic compounds with sulfonylhydrazones (Barluenga reaction).The new catalyst system and modulation of the electronic nature of hydrazone that were needed for successful reaction are described herein.
PREPARATION AND CHARACTERIZATION OF CHELATING MONOOLEFIN-ANILINE LIGANDS AND THEIR PLATINUM(II) COMPLEXES
Cooper, Mervyn K.,Yaniuk, Darryl W.
, p. 231 - 248 (2007/10/02)
A number of new chelating monoolefin-aniline ligands have been prepared and treated with platinum(II). 1H NMR spectra of the ligands and their platinum(II) complexes have been recorded in order to investigate the bonding between the platinum and the olefi
