104823-08-7Relevant articles and documents
ASYMMETRIC MICHAEL-TYPE ALKYLATION OF CHIRAL IMINES. ENANTIOSELECTIVE SYNTHESES OF (-)-GEOSMIN AND TWO OTHER RELATED NATURAL TERPENES, AS WELL AS ENANT-(+)-GEOSMIN
Revial, Gilbert
, p. 4121 - 4124 (2007/10/02)
Natural (-)-geosmin 11, (+)-octalone 14 (from Vetiveria zizanioides), and (+)-octalin 15 (from Bazzania fauriana and B. angustifolia) have been prepared in high chemical and enantiomeric yields via the asymmetric process involving Michael-type alkylation of chiral imines 6 and 12.Enant-(+)-geosmin has been also synthesized by the same procedure.