1048334-88-8

Basic information

• Product Name: 10-[4-(phenylsulfonylamino)-4-oxobutyryl]-11-(4-benzyloxy-2-chloro-phenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one
• Synonyms: 10-[4-(phenylsulfonylamino)-4-oxobutyryl]-11-(4-benzyloxy-2-chloro-phenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one
• CAS NO: 1048334-88-8
• Molecular Weight: 714.239
• Mol File: 1048334-88-8.mol

Chemical Properties

• CAS DataBase Reference: 10-[4-(phenylsulfonylamino)-4-oxobutyryl]-11-(4-benzyloxy-2-chloro-phenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 10-[4-(phenylsulfonylamino)-4-oxobutyryl]-11-(4-benzyloxy-2-chloro-phenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one(1048334-88-8)
• EPA Substance Registry System: 10-[4-(phenylsulfonylamino)-4-oxobutyryl]-11-(4-benzyloxy-2-chloro-phenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one(1048334-88-8)

Safety Data

• Hazardous Substances Data: 1048334-88-8(Hazardous Substances Data)

Upstream product

• 1048041-43-5 11-(4-benzyloxy-2-chlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one 
• 98-10-2 benzenesulfonamide 
• 1048334-86-6 4-[11-(4-benzyloxy-2-chlorophenyl)-6-hydroxy-3,3-dimethyl-1-oxo-1,2,3,4,5,11-hexahydrodibenzo[b,e][1,4]diazepin-10-yl]-4-oxobutyric acid 

Relevant articles and documents

6-HYDROXY-DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS

Inhibitors of HCV replication of formula (I) the stereoisomers, prodrugs, tautomers, racemics, salts, hydrates or solvates thereof wherein R1, R2; R3; R4a and R4b have the meaning defined in the claims.The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.