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1048041-43-5

11-(4-benzyloxy-2-chlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 11-(4-benzyloxy-2-chlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one

    Cas No: 1048041-43-5

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  • 1048041-43-5 Structure

  • Basic information

    1. Product Name: 11-(4-benzyloxy-2-chlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one
    2. Synonyms: 11-(4-benzyloxy-2-chlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one
    3. CAS NO:1048041-43-5
    4. Molecular Formula:
    5. Molecular Weight: 474.987
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1048041-43-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 11-(4-benzyloxy-2-chlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 11-(4-benzyloxy-2-chlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one(1048041-43-5)
    11. EPA Substance Registry System: 11-(4-benzyloxy-2-chlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one(1048041-43-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1048041-43-5(Hazardous Substances Data)

1048041-43-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1048041-43-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,8,0,4 and 1 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1048041-43:
(9*1)+(8*0)+(7*4)+(6*8)+(5*0)+(4*4)+(3*1)+(2*4)+(1*3)=115
115 % 10 = 5
So 1048041-43-5 is a valid CAS Registry Number.

1048041-43-5Downstream Products

1048041-43-5Relevant articles and documents

1,5-Benzodiazepine inhibitors of HCV NS5B polymerase

McGowan, David,Nyanguile, Origene,Cummings, Maxwell D.,Vendeville, Sandrine,Vandyck, Koen,Van den Broeck, Walter,Boutton, Carlo W.,De Bondt, Hendrik,Quirynen, Ludo,Amssoms, Katie,Bonfanti, Jean-Francois,Last, Stefaan,Rombauts, Klara,Tahri, Abdellah,Hu, Lili,Delouvroy, Frederic,Vermeiren, Katrien,Vandercruyssen, Genevieve,Van der Helm, Liesbet,Cleiren, Erna,Mostmans, Wendy,Lory, Pedro,Pille, Geert,Van Emelen, Kristof,Fanning, Gregory,Pauwels, Frederik,Lin, Tse-I,Simmen, Kenneth,Raboisson, Pierre

scheme or table, p. 2492 - 2496 (2009/12/07)

Optimization through parallel synthesis of a novel series of hepatitis C virus (HCV) NS5B polymerase inhibitors led to the identification of (R)-11-(4-benzyloxy-2-fluorophenyl)-6-hydroxy-3,3-dimethyl-10-(6-methylpyridine-2-carbonyl)-2,3,4,5,10,11-hexahydr

10-SULFONYL-DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS

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, (2008/12/08)

Inhibitors of HCV replication of formula (I) and the stereoisomers, prodrugs, tautomers, racemics, salts, hydrates or solvates thereof, wherein X, Y, R1; R2; R3; R4a and R4b have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.

6-HYDROXY-DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS

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Page/Page column 52-53; 176; 179, (2008/12/08)

Inhibitors of HCV replication of formula (I) the stereoisomers, prodrugs, tautomers, racemics, salts, hydrates or solvates thereof wherein R1, R2; R3; R4a and R4b have the meaning defined in the claims.The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.

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