1048367-35-6Relevant academic research and scientific papers
Novel 6-substituted benzothiazol-2-yl indolo[1,2-c]quinazolines and benzimidazo[1,2-c]quinazolines
Frère, Stéphane,Thiéry, Valérie,Bailly, Christian,Besson, Thierry
, p. 773 - 779 (2003)
The synthetic route to and a preliminary biological evaluation of novel indolo[1,2-c]quinazolines (8) and benzimidazo[1,2-c]quinazolines (9) are described. The products were obtained by condensation of the appropriate diamines (e.g. 2-(2-aminophenyl)indol
HETEROCYCLYLAMIDES AS GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS
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Page/Page column 83, (2009/03/07)
Compounds represented by formula (I) are inhibitors of gut microsomal triglyceride transfer protein. Such compounds are useful in treating diseases or conditions such as diabetes and obesity, along with patients are risk for developing such diseases or conditions.
Discovery of benzothiazole derivatives as efficacious and enterocyte-specific MTP inhibitors
Vu, Chi B.,Milne, Jill C.,Carney, David P.,Song, Jeffrey,Choy, Wendy,Lambert, Philip D.,Gagne, David J.,Hirsch, Michael,Cote, Angela,Davis, Meghan,Lainez, Elden,Meade, Nekeya,Normington, Karl,Jirousek, Michael R.,Perni, Robert B.
scheme or table, p. 1416 - 1420 (2009/11/30)
A series of triamide derivatives bearing a benzothiazole core is shown to be potent microsomal triglyceride transfer protein (MTP) inhibitors. In order to minimize liver toxicity, these compounds have been optimized to have activity only in the enterocyte
GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS
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Page/Page column 89-91, (2008/12/08)
Compounds represented by formula (I): are inhibitors of gut microsomal triglyceride transfer protein. Such compounds are useful in treating diseases or conditions such as diabetes and obesity, along with patients are risk for developing such diseases or conditions.
