104848-99-9

Basic information

• Product Name: D-Proline, 1-[N-[N-[(1,1-dimethylethoxy)carbonyl]-2-methylalanyl]-L-phenylalanyl]-, methyl ester
• CAS NO: 104848-99-9
• Molecular Formula: C24H35N3O6
• Molecular Weight: 461.558
• Mol File: 104848-99-9.mol

Chemical Properties

• CAS DataBase Reference: D-Proline, 1-[N-[N-[(1,1-dimethylethoxy)carbonyl]-2-methylalanyl]-L-phenylalanyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: D-Proline, 1-[N-[N-[(1,1-dimethylethoxy)carbonyl]-2-methylalanyl]-L-phenylalanyl]-, methyl ester(104848-99-9)
• EPA Substance Registry System: D-Proline, 1-[N-[N-[(1,1-dimethylethoxy)carbonyl]-2-methylalanyl]-L-phenylalanyl]-, methyl ester(104848-99-9)

Safety Data

• Hazardous Substances Data: 104848-99-9(Hazardous Substances Data)

Upstream product

• 192057-94-6 2-(tert-butoxycarbonylamino)isobutyryl-L-phenylalanine methyl ester 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 30992-29-1 Boc-Aib-OH 
• 1138156-33-8 Boc-Aib-Phe-OH 
• 2133-40-6 D-proline methyl ester hydrochloride 

Downstream Products

• 104849-05-0 cyclo[2-aminoisobutyryl-(S)-phenylalanyl-(R)-prolyl-(S)-2-aminosuberoyl-] 
• 52574-63-7 (5S,11S,13aR)-5-Benzyl-8,8-dimethyl-11-(6-oxo-oct-7-enyl)-decahydro-3a,6,9,12-tetraaza-cyclopentacyclododecene-4,7,10,13-tetraone 
• 53342-16-8 chlamydocin 
• 88643-73-6 chlamydocin 
• 88643-73-6 epi-chlamydocin 
• 104849-00-5 (R)-1-[(S)-2-(2-Amino-2-methyl-propionylamino)-3-phenyl-propionyl]-pyrrolidine-2-carboxylic acid methyl ester; compound with trifluoro-acetic acid 

Relevant articles and documents

Divergent Access to Histone Deacetylase Inhibitory Cyclopeptides via a Late-Stage Cyclopropane Ring Cleavage Strategy. Short Synthesis of Chlamydocin

A unified step-economical strategy for accessing histone deacetylase inhibitory peptides is proposed, based on the late-stage installation of multiple zinc-binding functionalities via the cleavage of the strained cyclopropane ring in the common pluripoten

Synthesis of chlamydocin by chelate-Claisen rearrangement

Chelate-Claisen rearrangement of a chiral allylic ester allows the synthesis of the unusual epoxyketo amino acid Aoe found in chlamydocin, one representative of a group of peptide-based HDAc inhibitors. Wiley-VCH Verlag GmbH & Co. KGaA, 2009.