104857-16-1Relevant articles and documents
A novel kind of dimmer (excimer)-induced-AIE compound 2- phenylisothiazolo[5,4-b]pyridin-3(2H)-one as high selective bisulfite anion probe
Yang, Bingchuan,Niu, Xiaoyi,Huang, Zixiao,Zhao, Cuihua,Liu, Yang,Ma, Chen
, p. 8250 - 8254 (2013)
An interesting dimmer (excimer)-induced-AIE characteristic of 2-phenylisothiazolo[5,4-b]pyridin-3(2H)-one was observed. By using a ring-opening reaction, we developed a novel fluorescent probe based on sub-micron particles of 2-phenylisothiazolo[5,4-b]pyridin-3(2H)-one in water.
Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs)
Gorsuch, Stephen,Bavetsias, Vassilios,Rowlands, Martin G.,Aherne, G. Wynne,Workman, Paul,Jarman, Michael,McDonald, Edward
experimental part, p. 467 - 474 (2009/07/25)
High-throughput screening led to the identification of isothiazolones 1 and 2 as inhibitors of histone acetyltransferase (HAT) with IC50s of 3 μM and 5 μM, respectively. Analogues of these hit compounds with variations of the N-phenyl group, and with vari
