10486-58-5

Usage

Uses

Used in Pharmaceutical Industry:
2-Mercaptobenzselenazole is used as a pharmaceutical agent for its potential therapeutic effects in treating various diseases. Its unique chemical structure allows it to interact with biological systems, offering a promising avenue for the development of new treatments.
Used as an Antioxidant:
2-Mercaptobenzselenazole is utilized as an antioxidant due to its ability to neutralize free radicals and protect cells from oxidative damage. This property makes it valuable in the prevention and treatment of conditions associated with oxidative stress.
Used in Antimicrobial Applications:
In the field of microbiology, 2-Mercaptobenzselenazole is used as an antimicrobial agent, leveraging its capacity to inhibit the growth of harmful microorganisms, thereby contributing to the development of new antimicrobial strategies.
Used in Antiparasitic Applications:
2-Mercaptobenzselenazole also serves as an antiparasitic agent, targeting parasites that cause various diseases. Its effectiveness in this area could lead to advancements in treatments for parasitic infections.
Used in Material Science:
2-MERCAPTOBENZSELENAZOLE is employed in the development of new materials and chemical processes, capitalizing on its unique structural and chemical properties to create innovative products with enhanced performance.
Each of these applications underscores the versatility and importance of 2-Mercaptobenzselenazole in multiple scientific and industrial domains.

InChI:InChI=1/C7H5NSSe/c9-7-8-5-3-1-2-4-6(5)10-7/h1-4H,(H,8,9)

Upstream product

• 75-15-0 carbon disulfide 
• 35350-43-7 bis(o-nitrophenyl) diselenide 
• 13037-60-0 1-bromo-2-isothiocyanatobenzene 
• 88-74-4 2-nitro-aniline 
• 365-33-3 2-nitrobenzenediazonium tetrafluoroborate 
• 51694-22-5 ortho-nitrophenyl selenocyanate 

Downstream Products

• 1171123-68-4 4-(1,3-benzoselenazol-2-ylthio)-3-methyl-5-oxo-N-phenyl-2,5-dihydro-1H-pyrazol-1-carboxamide 
• 1171123-62-8 C₁₉H₁₈N₄O₃SSe 
• 109496-75-5 (3-methyl-3H-benzoselenazol-2-ylidene)-(4-nitro-benzylidene)-hydrazine 

Relevant academic research and scientific papers

Synthesis of diselenadiazafulvalenes and influence of steric strain on their anodic behavior

A novel family of π-donor molecules, the diselenadiazafulvalenes (DSeDAFs), is presented. The synthetic approach to these donors, from o-nitroaniline, allows the formation of N,N′-dimethyldibenzo DSeDAF and N,N′-ethylenedibenzo DSeDAF. Comparative electrochemical study of these π-donor molecules demonstrates their excellent donor ability and the stabilizing effect of the ethylene bridge on the cation radical species.

Route towards diselenadiazafulvalenes

The first diselenadiazafulvalene has been chemically synthesised and electrochemically characterised, it presents similar air sensitiveness to its sulfur analogue and affords a spiroamide derivative upon oxidation as confirmed by its crystal structure.

The Importance of 1,5-Oxygen???Chalcogen Interactions in Enantioselective Isochalcogenourea Catalysis

The importance of 1,5-O???chalcogen (Ch) interactions in isochalcogenourea catalysis (Ch=O, S, Se) is investigated. Conformational analyses of N-acyl isochalcogenouronium species and comparison with kinetic data demonstrate the significance of 1,5-O???Ch interactions in enantioselective catalysis. Importantly, the selenium analogue demonstrates enhanced rate and selectivity profiles across a range of reaction processes including nitronate conjugate addition and formal [4+2] cycloadditions. A gram-scale synthesis of the most active selenium analogue was developed using a previously unreported seleno-Hugerschoff reaction, allowing the challenging kinetic resolutions of tertiary alcohols to be performed at 500 ppm catalyst loading. Density functional theory (DFT) and natural bond orbital (NBO) calculations support the role of orbital delocalization (occurring by intramolecular chalcogen bonding) in determining the conformation, equilibrium population, and reactivity of N-acylated intermediates.

A convenient synthesis of 2-sulfanylbenzoselenazole derivatives via the reaction of 2-lithiophenyl isothiocyanates with selenium

The title compounds have been prepared from 2-bromophenyl isothiocyanates 1. Thus, 2-lithiophenyl isothiocyanates 2, obtained from 1 and BuLi through Br/Li exchange, reacted with Se at -78° to form lithium benzoselenazole-2- thiolates 3, which, upon aqueo

Meso-ionic se- and s-containing tetrazoles

This invention relates to meso-ionic tetrazole compounds of the formula: STR1 wherein X- is -S- or -Se- which are useful as photographic additives and to an intermediate useful in the preparation thereof having the formula: STR2