104871-67-2

Basic information

• Product Name: Cyclohexanone, 2-[(R)-(4-methylphenyl)sulfinyl]-
• CAS NO: 104871-67-2
• Molecular Formula: C13H16O2S
• Molecular Weight: 236.335
• Mol File: 104871-67-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Cyclohexanone, 2-[(R)-(4-methylphenyl)sulfinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone, 2-[(R)-(4-methylphenyl)sulfinyl]-(104871-67-2)
• EPA Substance Registry System: Cyclohexanone, 2-[(R)-(4-methylphenyl)sulfinyl]-(104871-67-2)

Safety Data

• Hazardous Substances Data: 104871-67-2(Hazardous Substances Data)

Upstream product

• 66536-78-5 (+)-(R)-1-(p-tolylsulfinyl)-2-propanone 
• 56742-98-4 1-<(4-methylphenyl)sulphinyl>propan-2-one 
• 1200-13-1 1-(p-tolylsulfanyl)propan-2-one 
• 127642-05-1 6-Iodo-1-((R)-toluene-4-sulfinyl)-hexan-2-one 
• 108-94-1 cyclohexanone 
• 91796-57-5 4-Methyl-benzenesulfinic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 672-78-6 methyl p-toluene sulfinate 
• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 10424-93-8 N'-cyclohexylidene-N,N-dimethyl-hydrazine 
• 83859-16-9 N,N-Dimethyl-N'-[2-((R)-toluene-4-sulfinyl)-cyclohex-(E)-ylidene]-hydrazine 

Downstream Products

• 140710-35-6 (+)-(R)-3-methyl-2-p-tolylsulfenyl-2-cyclohexenyl trifluoroacetate 
• 140710-31-2 (R)-2-p-tolylsulfenyl-2-cyclohexenyl acetate 
• 140710-30-1 (S)-2-p-tolylsulfenyl-2-cyclohexenyl acetate 
• 140710-34-5 (S)-2-p-Tolylsulfanyl-cyclohex-2-enol 
• 140710-33-4 (R)-2-p-Tolylsulfanyl-cyclohex-2-enol 
• 185613-06-3 (S)-2-((1S,2S)-1-Hydroxy-2-p-tolylsulfanyl-cyclohexyl)-propionic acid ethyl ester 
• 185613-12-1 (R)-5-Hydroxy-2-[(1S,2S)-1-hydroxy-2-((R)-toluene-4-sulfinyl)-cyclohexyl]-pentanoic acid ethyl ester 
• 220033-64-7 [(R)-1-Hydroxy-2-((S)-toluene-4-sulfinyl)-2-p-tolylsulfanyl-cyclohexyl]-acetic acid ethyl ester 
• 220033-67-0 [(S)-1-Hydroxy-2-isopropylsulfanyl-2-((S)-toluene-4-sulfinyl)-cyclohexyl]-acetic acid ethyl ester 

Relevant articles and documents

Behaviour of 2-p-tolylsulfinyl cyclohexanols under the pummerer reaction conditions

The reactions of the chiral 2-p-tolylsulfinyl cyclohexanols with Ac2O/NaOAc (or (CF3CO)2O/Py) at r.t. yielded the 2-p-tolylsulfenyl-2-cyclohexenyl acetates, which cannot be hydrolyzed into the α-hydroxyketones. The 1-methy

A NOVEL AND USEFUL SYNTHETIC WAY TO CHIRAL α-SULFINYL CYCLIC KETONES BY THE ACID-CATALYZED REACTION OF ENOL SILYL ETHERS OF CYCLIC KETONES WITH CHIRAL SULFINATES

The acid-catalyzed reactions of enol silyl ethers of cyclic ketones with chiral sulfinic esters provided a new and general entry to optically active α-sulfinyl ketones.Reaction of the enol silyl ether of cyclohexanone with methyl (S)-p-toluenesulfinate in the presence of boron trifluoride etherate (2.0 equiv.) produced (RS)-2-p-toluenesulfinylcyclohexanone with inversion of configuration in 98.3 percent stereospecifity at the sulfur atom.This method was applicable smoothly to enol silyl ethers of other cyclic ketones with high stereospecifity.