104886-15-9

Upstream product

• 14062-18-1 ethyl p-methoxyphenylacetate 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 23197-67-3 diethyl 2-(4-methoxyphenyl)malonate 
• 104886-05-7 C₁₇H₁₉NO₅ 
• 104886-08-0 1-diazo-3-(4'-methoxyphenyl)-4-(pyrrol-1-yl)-2-butanone 
• 73048-98-3 1-aza-3-(4-methoxyphenyl)bicyclo<4.3.0>-5-nonen-4-one 
• 104886-12-6 5,6-dihydro-6-(4'-methoxyphenyl)-7(8H)-indolizinone 
• 104886-17-1 2-(4'-methoxyphenyl)-3-(pyrrol-1-yl)propionic acid 
• 39729-00-5 2-(4-methoxyphenyl)propenoic acid ethyl eter 

Relevant academic research and scientific papers

Intramolecular Carbenoid Reactions of Pyrrole Derivatives. A Total Synthesis of (+/-)-Ipalbidine

A mew method for alkaloid synthesis is described.The rhodium(II)-acetate-catalyzed decomposition of 3-(4-acetoxyphenyl)-1-diazo-4-(pyrrol-1-yl)-2-butanone (5d) gave 6-(4-acetoxyphenyl)-5,6-dihydro-7(8H)-indolizinone (6d) in 82percent yield via an intramolecular carbenoid reaction.The latter compound was converted in four steps in 13percent overall yield to (+/-)-ipalbidine (1b).

The synthesis of phenolic propane-1, 2- and 1,3-diols as intermediates in immobilised chelatants for the borate anion

The isomeric 3-(hydroxyphenyl)propane-1, 2-diols have been synthesised from allylic precursors by epoxidation and cleavage. Several different methods have been examined for obtaining 1-(methoxyphenyl)propane-1, 3-diols. 2-(methoxyphenyl)propane-1, 3-diols and certain hydroxy analogues have been obtained from benzaldoximes converted by oxidation to methoxy- and benzyloxynitromethylbenzenes followed by hydroxymethylation with formaldehyde and catalytic hydrogenation.

COMPETITIVE INTRAMOLECULAR CARBENOID REACTIONS OF PYRROLE DERIVATIVES

Rhodium(II) acetate-catalyzed decomposition of 1-diazo-3-phenyl-4-(pyrrol-1-yl)-butan-2-one and its p-methoxy derivative resulted in their intramolecular cyclization to form the 6-phenyl-5,6-dihydroindolizin-7(8H)-ones and 1-(pyrrol-1-yl)methylindan-3-ones as major and minor products respectively in high yields (77-89percent).The p-nitrophenyldiazo compound cyclized exclusively to the 5,6-dihydroindolizin-7(8H)-one in 76percent yield.