104891-35-2

Upstream product

• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 96-34-4 methyl chloroacetate 
• 105-39-5 chloroacetic acid ethyl ester 
• 5056-07-5 (S)-methyl p-tolyl sulfoxide 

Downstream Products

• 175878-62-3 (R)-2-Chloromethyl-2-((R)-toluene-4-sulfinylmethyl)-oxirane 
• 92210-74-7 (E)-3-((R)-Toluene-4-sulfinyl)-prop-2-en-1-ol 
• 92210-76-9 (S_S)-3-[(4-methylphenyl)sulfinyl]furan-2(5H)-one 
• 197848-99-0 (1R,2R,6S,7S)-2-((S)-Toluene-4-sulfinyl)-4-oxa-tricyclo[5.2.1.0^2,6]dec-8-en-3-one 
• 175878-79-2 (2R,R_S)-3-chloro-2-<<4-(methylphenyl)sulfinyl>methyl>propan-1,2-diol 

Relevant academic research and scientific papers

Synthesis and reactions of enantiomerically pure chloromethyl oxiranes

The reactivities of 1-chloro-3-p-tolylsulfinyl acetone (R(S))-1 towards diazomethane and of the resulting diastereoisomeric 1-chloromethyl-1-sulfinylmethyl oxiranes 2 towards O-, N-, and C-centred nucleophiles are investigated. The synthesis of differentl

Dienophilic behavior of (S)-2-p-tolylsulfinyl butenolide

The study of the reactions of (S)-2-p-tolylsulfinyl butenolide (2) with cyclic and acyclic dienes is reported. The reactivity and stereoselectivity of this dienophile is compared with those of (S)-2-p-tolylsulfinyl cyclopentenone (3) in order to obtain information about the stereochemical models so far proposed.

Asymmetric Synthesis of the C-1-C-8 Fragment of Leukotriene B4 and C-11-C-20 Fragments of Leukotriene B4 and 12(S)-Hydroxy-5,8,14(Z), 10(E) Eicosatetraenoic Acid

An asymmetric synthesis of the C-1-C-8 fragment of LTB4 based on the reduction of optically active β-ketosulfoxides is described as well as the asymmetric synthesis of the C-11-C-20 fragments of LTB4 and 12(S)-hydroxy-5,8,14(Z), 10(E

NEW CHIRONS FOR THE SYNTHESIS OF FLUORINE-CONTAINING ORGANIC COMPOUNDS. HOMOCHIRAL 3--1,1,1-TRIHALO-PROPAN-2-ONES, -PROPAN-2-OLS AND -PROPAN-2-OL ALKENYL ETHERS

The condensation of the lithium derivative of methyl 4-methylphenyl (S)-(-)-sulphoxide, 1, with ethyl esters of 1-fluoro-, 1-chloro-, 1-chloro-1,1-difluoro-, 1-bromo-1,1-difluoro- and 1,1-dichloro-1-fluoro-acetic acids, 2a-e, respectively, afforded enanti

OPTICALLY ACTIVE α-SULFINYL EPOXIDES: PRECURSORS OF CHIRAL FUNCTIONALIZED HOMOALLYLIC ALCOHOLS

An asymmetric synthesis of chiral functionalized homoallylic alcohols in both configurations is described from the corresponding optically active α-sulfinyl epoxides.

SYNTHESIS OF OPTICALLY PURE α-HALO-α'-SULPHINYL-KETONES

When optically pure sulphinyl carbanions are reacted at -75 deg C with α-chloro or α-bromo carboxylic acid esters addition on the carboxyl group occurs and corresponding α-halo-α'-sulphinyl-ketones are obtained in optically pure form.